Breast Cancer - Arab Medical Association Against Cancer

Prognostic Factors 217Table 14.6. Predictive factors of response to CT for 89 large carcinomas (>3 cm)Parameters N Clinical regression P valueTNMT2 45 59%T3 36 58% NST4 8 41%Rapid growth**PEV0 61 53%PEV1 28 67% P=0.02Menopausal statusPremenopausal 42 64%Postmenopausal 47 51% P=0.03Histologic typeductal carcinoma 83 62%lobular carcinoma 5 39% NSin situ ductal carcinoma 1Histoprognostic gradeI 4 58%II 44 52% NSIII 38 63%Mitosis (SBR)*1 26 49%2 14 47% 0.023 46 65%Not evaluated 3Fibrosis0 4 86%1 52 61% < 0.032 30 50%Necrosis0 60 52%1 10 72% < 0.032 15 67%*1 + 2 vs. 3 p= 0.005**PEV1= rapid clinical evolution (subjective clinical growth in 6 months) Denoix 1970