18.1 Studying Viruses and Prokaryotes

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In some viruses, capsids form a 20-sided polyhedral. Rodshapedand strandlike viruses often have capsids shaped in coils,like a spring or helix.In contrast to prokaryotes and eukaryotes, in which DNA isalways the main genetic material, a virus can have either DNA orRNA but never both. The genetic material of viruses can be singlestrandedor double-stranded, and linear, circular, or segmented.Viruses that Infect BacteriaOne group of viruses is the bacteriophages, often called simply“phages.” Bacteriophages (bak-TEER-ee-uh-fayj-ihz) are virusesthat prey on bacteria. One example is the T-bacteriophage thatinfects Escherichia coli, the bacteria commonly found in the intestinesof mammals. The T-bacteriophage shown in FIGURE 18.5 has a 20-sidedcapsid connected to a long protein tail with spiky footlike fibers. The capsidcontains the genetic material. The tail and its spikes help attach the virus tothe host cell. After attachment, the bacteriophage’s tail releases an enzyme thatbreaks down part of the bacterial cell wall. The tail sheath contracts, and thetail core punches through the cell wall, injecting the phage’s DNA. The phageworks like a syringe, injecting its genes into the host cell’s cytoplasm, where itsDNA is found.colored SEM; magnifications:large photo 25,000; inset 38,000FIGURE 18.5 The SEM aboveshows bacteriophages attackingan E. coli bacterium. While injectingtheir genetic material into thebacterium, the protein coatsremain outside the cell (inset). Theunique structure of a bacteriophageis shown below.capsidViruses that Infect EukaryotesViruses that prey on eukaryotes differ from bacteriophages in their methodsof entering the host cell. For example, these viruses may enter the cells byendocytosis. Recall from Chapter 3 that endocytosis is an active method ofbringing molecules into a cell by forming vesicles, or membrane-bound sacs,around the molecules. If the viruses are enveloped, they can also enter a hostcell by fusing with the plasma membrane of the host cell and releasing thecapsid into the cell’s cytoplasm. HIV is a virus that enters cells in this way.Once inside the cell, eukaryotic viruses target the nucleus of the cell.Summarize Describe how the structures of a bacteriophage are well-suitedfor their functions.DNAtail fibertail sheathMAIN IDEAViruses cause two types of infections.The ways in which viruses enter and leave a cell may vary, but two basicpathways of infection are similar for all viruses. These pathways are shown forthe most studied viruses, the bacteriophages, in FIGURE 18.6.Once inside the host cell, phages follow one of two general paths in causingdisease. In one path, the phage behaves like a bad houseguest. It takes over thehousehold, eats all of the food in the refrigerator, and then blows up the housewhen it leaves. The other path of infection is somewhat more subtle. Insteadof destroying the house, the phage becomes a permanent houseguest. Neitherpath is good for the host.Chapter 18: Viruses and Prokaryotes 549
FIGURE 18.6 General Pathways of Viral InfectionA lytic infection results in the lysis, or breaking apart, of the host cell andrelease of new viral particles. A lysogenic infection does not destroy thehost cell.BIOLOGYExamine the twoways in which virusesinfect host cells atClassZone.com.host bacteriumLYTIC INFECTIONThe bacteriophage attachesand injects its DNA into ahost bacterium.The host bacterium breaks apart,or lyses. Bacteriophages are ableto infect new host cells.The viral DNAforms a circle.The viral DNA directs the hostcell to produce new viral parts.The parts assemble into newbacteriophages.The virus may enter thelysogenic cycle, in which thehost cell is not destroyed.LYSOGENIC INFECTIONThe prophage may leave thehost’s DNA and enter thelytic cycle.The viral DNA is called a prophagewhen it combines withthe host cell’s DNA.Many cell divisions produce acolony of bacteria infectedwith prophage.Although the prophage is notactive, it replicates along withthe host cell’s DNA.CRITICALVIEWINGWhy are no capsids or tail sheaths made duringa lysogenic infection?550 Unit 6: Classification and Diversity
Page 2 and 3: How are bacteriahelpful to humans?c
Page 4 and 5: FIGURE 18.2 Relative Sizes of Cells
Page 6 and 7: 18.2Viral Structure andReproduction
Page 10 and 11: Lytic InfectionA lytic infection (L
Page 12 and 13: Influenza Winter usually causes con
Page 14 and 15: 18.4Bacteria and ArchaeaKEY CONCEPT
Page 16 and 17: FIGURE 18.13 Prokaryote StructureTh
Page 18 and 19: 18.5Beneficial Rolesof ProkaryotesK
Page 20 and 21: Recall from Chapter 13 that nitroge
Page 22 and 23: 18.6Bacterial Diseasesand Antibioti
Page 24 and 25: MAIN IDEABacteria can evolve resist
Page 26 and 27: INVESTIGATIONModeling VirusesThe st
Page 28 and 29: Chapter AssessmentChapter Vocabular
Page 30: For more test practice,go to ClassZ

18.1 Studying Viruses and Prokaryotes

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