Inotropes and vasopressores - Cardiff PICU

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Definition of ShockInadequate oxygen delivery totissues to meet dem<strong>and</strong> becauseof circulatory failure
Page 4 and 5: PhysiologyO 2 delivery = (1.34 × H
Page 6 and 7: Physiology - fluid filled circuit a
Page 8 and 9: Flow needs to be adequate forPerfus
Page 10: Treatment goals◦ Improve oxygenat
Page 13: Outcome?U of M 1969 Medicine 48: 30
Page 19 and 20: Efficacy variable Placebo N=235 ∗
Page 21 and 22: Fluid resuscitation
Page 23 and 24: Severe sepsis - Outcomes (9625 case
Page 25 and 26: RESULTS.34 patients (median age, 13
Page 27 and 28: CONCLUSIONRapid fluid resuscitation
Page 32 and 33: Figure 3. Type of fluid administere
Page 34 and 35: Inotropes and pressors◦ Advantage
Page 36 and 37: Available inotropes and pressors◦
Page 38 and 39: Catecholamine synthesis
Page 40 and 41: Dopamine◦ Precursor of noradrenal
Page 42 and 43: Noradrenaline◦ α1 and β1, with
Page 44 and 45: Phosphodiesterase inhibitors◦ Eno
Page 46: Vasopressin◦ Initially high endog
Page 49 and 50: Which inotropes when?
Page 51: Benefit from individualised resusci
Page 54:
Shock should be clinically diagnose
Page 64:
A Comparison of ACCM-PALS Guideline
Page 68 and 69:
◦ Case control study of fatal vs.
Page 70 and 71:
Common errors (1)◦ Failure to est
Page 72 and 73:
Common errors (2)◦ Inadequate flu
Page 74 and 75:
Common errors (3)◦ KCl boluses◦
Page 76:
Summary◦ Volume◦ Inotropes◦ A
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Inotropes and vasopressores - Cardiff PICU

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