Inotropes and vasopressores - Cardiff PICU

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Vasopressin◦ Initially high endogenousvasopressin in septic shock <strong>and</strong>haemorrhagic shock◦ Secretion normally stimulated byhypovolaemia <strong>and</strong> hypotension◦ Prolonged hypotension or septicshock levels decrease
Page 2: Definition of ShockInadequate oxyge
Page 5 and 6: Physiology◦ Adult Oxygen demand 1
Page 7 and 8: Compensation◦ Increase cardiac ou
Page 9 and 10: Pathophysiology of Sepsis◦ Endoth
Page 12 and 13: A brief history of septic shock tre
Page 15: The search for a magic bulletFew Ra
Page 20 and 21: esolve 28-day MortalityAdditional S
Page 22 and 23: Shock:GastroenteritisAbdo obstructi
Page 24 and 25: Role of early fluid resuscitation i
Page 26 and 27: RESULTS.34 patients (median age, 13
Page 28: 7000 critically ill adults
Page 33 and 34: Inotropes and pressors
Page 35 and 36: When to start inotropes◦ Sepsis -
Page 37 and 38: Choice of inotrope◦ Personal pref
Page 39 and 40: Receptor2 ndmessengerActionsα 1IP
Page 41 and 42: Adrenaline◦ α 1 , β 1 , β 2 .
Page 43 and 44: Dobutamine◦ Synthetic mixture of
Page 45: Phosphodiesterase inhibitors◦ Eno
Page 49 and 50: Which inotropes when?
Page 51: Benefit from individualised resusci
Page 54: Shock should be clinically diagnose
Page 64: A Comparison of ACCM-PALS Guideline
Page 68 and 69: ◦ Case control study of fatal vs.
Page 70 and 71: Common errors (1)◦ Failure to est
Page 72 and 73: Common errors (2)◦ Inadequate flu
Page 74 and 75: Common errors (3)◦ KCl boluses◦
Page 76: Summary◦ Volume◦ Inotropes◦ A

Inotropes and vasopressores - Cardiff PICU

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