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A Randomized Trial of Thymoglobulin to Prevent Chronic ... - CBMTG

A Randomized Trial of Thymoglobulin to Prevent Chronic ... - CBMTG

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Management <strong>of</strong> EBV• Be aware <strong>of</strong> the possibility; watch for FUO andlymphadenopathy.• Perform QPCR for EBV weekly until day 100• If QPCR shows activation, consider decreasingimmunosuppression.• If symp<strong>to</strong>ms are compatible:– Have a low threshold for imaging and biopsy– Exclude alternative diagnoses– Give rituximab weekly until symp<strong>to</strong>ms and copy number normalize.– Consider DLI if donor EBV antibody-positive.

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