A Randomized Trial of Thymoglobulin to Prevent Chronic ... - CBMTG
A Randomized Trial of Thymoglobulin to Prevent Chronic ... - CBMTG
A Randomized Trial of Thymoglobulin to Prevent Chronic ... - CBMTG
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FinkeLancet Oncol 2009;10: 855–64BacigalupoBlood 2001;98:2942BBMT 2006;12:560ATG-Fresenius60 mg/kg <strong>to</strong>tal<strong>Thymoglobulin</strong>Low-dose7.5 mg/kg <strong>to</strong>tal<strong>Thymoglobulin</strong>High-dose15 mg/kg <strong>to</strong>talPrimary End-Point Death/AGVHD III-IV AGVHD III-IVPrimary End-Point NS NS 11% vs 50%, P=.001Infectious Deaths NS NS 30% vs 7%Survival NS NS NSNon RelapseMortality<strong>Chronic</strong> GVHD 30.8% vs 58.8%p
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