Monitoring Regional Oxygen Saturation - Casecag.com

Cerebral oxygen desaturation predicts cognitive decline and longerhospital stay after cardiac surgery.Slater JP, Guarino T, Stack J, et al.Study Design:• Prospective, randomized, controlled,blinded trial in a coronary artery bypassgrafting (CABG) population.– Jan 2004-Feb 2006, n=265 CABG patientsutilizing cardiopulmonary bypass. (n=115control group; n=125 intervention group)Objective:• Examine and describe a relationshipbetween intraoperative cerebral oxygendesaturation and adverse events such asneurocognitive decline and increased lengthof stay.Conclusion :• Intraoperative cerebral oxygen desaturationis significantly associated with an increasedrisk of cognitive decline (OR 2.2; 95% CI[1.11, 4.45], P = 0.024) and prolongedhospital stay (OR 2.71; 95% CI [1.31,5.6], P= 0.007). Mitigating cerebral desaturationsmay reduce these risks.Ann Thorac Surg. 2009;87(1):36-44.