and Incomplete Septal Cirrhosis
Non-cirrhotic portal hypertension & incomplete septal cirrhosis
Non-cirrhotic portal hypertension & incomplete septal cirrhosis
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Primary Hepatic Vascular Diseases associated with Portal Hypertension<br />
(Non - Cirrhotic )<br />
Site of vessel Pathological changes Clinical Syndromes<br />
Portal vein<br />
(large)<br />
Thrombosis<br />
Portal vein thrombosis<br />
Portal vein<br />
(small)<br />
Sinusoid<br />
Hepatic vein<br />
(small)<br />
Hepatic vein<br />
(large)<br />
Obliteration/loss<br />
• possibly related to previous<br />
thrombosis<br />
(“hepato-portal sclerosis”)<br />
Endothelial injury<br />
• usually caused by toxins<br />
(dilatation/congestion)<br />
Endothelial injury<br />
• usually caused by toxins<br />
(luminal occlusion)<br />
Thrombosis<br />
“Idiopathic” non-cirrhotic<br />
portal hypertension<br />
“Sinusoidal obstruction<br />
syndrome”<br />
Hepatic veno-occlusive<br />
disease<br />
Budd-Chiari syndrome
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