Cell Nucleus

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How Transcription Factors Work Binds to the response elements in the Distal promoter region (recognizes the nucleotide base sequence) Recruits proteins which help the preinitiation complex work. These are called Coactivators. Enhances the RNA polymerase activity Thursday, January 21, 2010 15
More on Coactivators Coactivators are proteins which link transcription factors, including the glucocorticoid receptor to general transcription factors needed for transcription Chromatin re-modeling enzymes For the glucocorticoid receptor the coactivator protein is called CBP coactivator, a type of Histone Acetyltransferase (HAT) 16 Thursday, January 21, 2010
Page 1 and 2: Cell Nucleus Gene Structure Control
Page 3 and 4: - Entire genome in each cell. How d
Page 5 and 6: Transcriptional Control RNA polyme
Page 7 and 8: Components of the Promoter B. Proxi
Page 9 and 10: Components of the Promoter D) Enhan
Page 11 and 12: The Glucocorticoid Receptor Glucoco
Page 13 and 14: Response Elements on the PEPCK Gene
Page 15: Question: How do transcription fact
Page 19 and 20: Histone Acetyltransferase: Step I C
Page 21 and 22: Transcriptional Repression: Histone
Page 23 and 24: DNA Methyltransferases Add methyl
Page 25 and 26: Methylated sites promote gene inact
Page 27 and 28: Main levels of gene expression 1. G

Cell Nucleus

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