An Introduction to the Endocrine System
An Introduction to the Endocrine System
An Introduction to the Endocrine System
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Thyroid Hormone Syn<strong>the</strong>sis<br />
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.<br />
Thyroid follicle<br />
Blood capillary<br />
Transport<br />
proteins<br />
I −<br />
Iodide<br />
1 Iodide absorption and oxidation<br />
5<br />
1<br />
Follicle cell<br />
2 Thyroglobulin syn<strong>the</strong>sis and secretion<br />
T 3<br />
T 4<br />
3 Iodine added <strong>to</strong> tyrosines of thyroglobulin<br />
4<br />
Thyroglobulin uptake and hydrolysis<br />
Lysosome<br />
4<br />
I –<br />
2<br />
Thyroglobulin<br />
5 Release of T 4 and a small amount of T 3 in<strong>to</strong><br />
<strong>the</strong> blood<br />
I *<br />
Iodine<br />
S<strong>to</strong>red<br />
thyroglobulin<br />
3