An Introduction to the Endocrine System
An Introduction to the Endocrine System
An Introduction to the Endocrine System
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Hormone Recep<strong>to</strong>rs<br />
• hormones stimulate only those cells that have<br />
recep<strong>to</strong>rs for <strong>the</strong>m<br />
• recep<strong>to</strong>rs are protein or glycoprotein molecules:<br />
– on plasma membrane, in <strong>the</strong> cy<strong>to</strong>plasm, or in <strong>the</strong><br />
nucleus<br />
• recep<strong>to</strong>rs act like switches turning on metabolic<br />
pathways when hormone binds <strong>to</strong> <strong>the</strong>m<br />
• usually each target cell has a few thousand<br />
recep<strong>to</strong>rs for a given hormone<br />
• recep<strong>to</strong>r-hormone interactions exhibit specificity<br />
and saturation<br />
– specific recep<strong>to</strong>r for each hormone<br />
– saturated when all recep<strong>to</strong>r molecules are occupied by<br />
hormone molecules
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