Bax and APPL1 are involved in DCC-ADD induced colorectal ...
Bax and APPL1 are involved in DCC-ADD induced colorectal ...
Bax and APPL1 are involved in DCC-ADD induced colorectal ...
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
Acknowledgement<br />
This study was supported by the National Natural<br />
Science Foundation of Ch<strong>in</strong>a (No. 30801354 <strong>and</strong><br />
References<br />
Banerjee AK. <strong>DCC</strong> expression <strong>and</strong> prognosis <strong>in</strong> <strong>colorectal</strong><br />
cancer. Lancet. 1997 Apr 5;349(9057):968.<br />
Bernet A, Mehlen P. Dependence receptors: when apoptosis<br />
controls tumor progression. Bull Cancer. 2007<br />
Apr;94(4):E12-7.<br />
Castets M, Broutier L, Mol<strong>in</strong> Y, Brevet M, Chazot G, Gadot N,<br />
Paquet A, Mazel<strong>in</strong> L, Jarrosson-Wuilleme L,<br />
Scoazec JY, Bernet A, Mehlen P. <strong>DCC</strong> constra<strong>in</strong>s<br />
tumour progression via its dependence receptor<br />
activity. Nature. 2011 Dec 11;482(7386):534-7.<br />
Fearon ER, Cho KR, Nigro JM, Kern SE, Simons JW, Ruppert<br />
JM, Hamilton SR, Preis<strong>in</strong>ger AC, Thomas G, K<strong>in</strong>zler<br />
KW, et al. Identification of a chromosome 18q gene<br />
that is altered <strong>in</strong> <strong>colorectal</strong> cancers. Science. 1990<br />
Jan 5;247(4938):49-56.<br />
Forcet C, Ye X, Granger L, Corset V, Sh<strong>in</strong> H, Bredesen DE,<br />
Mehlen P. The dependence receptor <strong>DCC</strong> (deleted <strong>in</strong><br />
<strong>colorectal</strong> cancer) def<strong>in</strong>es an alternative mechanism<br />
for caspase activation. Proc Natl Acad Sci U S A.<br />
2001 Mar 13;98(6):3416-21.<br />
Gal R, Sadikov E, Sulkes J, Kle<strong>in</strong> B, Koren R. Deleted <strong>in</strong><br />
<strong>colorectal</strong> cancer prote<strong>in</strong> expression as a possible<br />
predictor of response to adjuvant chemotherapy <strong>in</strong><br />
<strong>colorectal</strong> cancer patients. Dis Colon Rectum. 2004<br />
Jul;47(7):1216-24.<br />
Goyette MC, Cho K, Fasch<strong>in</strong>g CL, Levy DB, K<strong>in</strong>zler KW,<br />
Paraskeva C, Vogelste<strong>in</strong> B, Stanbridge EJ.<br />
Progression of <strong>colorectal</strong> cancer is associated with<br />
multiple tumor suppressor gene defects but <strong>in</strong>hibition<br />
of tumorigenicity is accomplished by correction of<br />
any s<strong>in</strong>gle defect via chromosome transfer. Mol Cell<br />
Biol. 1992 Mar;12(3):1387-95.<br />
Horstmann MA, Pösl M, Scholz RB, Anderegg B, Simon P,<br />
Baumgaertl K, Dell<strong>in</strong>g G, Kabisch H. Frequent<br />
reduction or loss of <strong>DCC</strong> gene expression <strong>in</strong> human<br />
osteosarcoma. Br J Cancer. 1997;75(9):1309-17.<br />
Gene Therapy <strong>and</strong> Molecular Biology Vol 14, page 59<br />
61<br />
30970791) <strong>and</strong> the Fundamental Research Funds<br />
(201103234) from Jil<strong>in</strong> University, Ch<strong>in</strong>a<br />
Lalier L, Cartron PF, Ju<strong>in</strong> P, Nedelk<strong>in</strong>a S, Manon S, Bech<strong>in</strong>ger<br />
B, Vallette FM. <strong>Bax</strong> activation <strong>and</strong> mitochondrial<br />
<strong>in</strong>sertion dur<strong>in</strong>g apoptosis. Apoptosis. 2007<br />
May;12(5):887-96.<br />
Liu J, Yao F, Wu R, Morgan M, Thorburn A, F<strong>in</strong>ley RL Jr,<br />
Chen YQ. Mediation of the <strong>DCC</strong> apoptotic signal by<br />
DIP13 alpha. J Biol Chem. 2002 Jul<br />
19;277(29):26281-5.<br />
Mazel<strong>in</strong> L, Bernet A, Bonod-Bidaud C, Pays L, Arnaud S,<br />
Gespach C, Bredesen DE, Scoazec JY, Mehlen P.<br />
Netr<strong>in</strong>-1 controls <strong>colorectal</strong> tumorigenesis by<br />
regulat<strong>in</strong>g apoptosis. Nature. 2004 Sep<br />
2;431(7004):80-4.<br />
Mehlen P, Rabizadeh S, Snipas SJ, Assa-Munt N, Salvesen<br />
GS, Bredesen DE. The <strong>DCC</strong> gene product <strong>in</strong>duces<br />
apoptosis by a mechanism requir<strong>in</strong>g receptor<br />
proteolysis. Nature. 1998 Oct 22;395(6704):801-4.<br />
Mehlen P, Fearon ER. Role of the dependence receptor <strong>DCC</strong> <strong>in</strong><br />
<strong>colorectal</strong> cancer pathogenesis. J Cl<strong>in</strong> Oncol. 2004<br />
Aug 15;22(16):3420-8.<br />
Narayanan R, Lawlor KG, Schaapveld RQ, Cho KR,<br />
Vogelste<strong>in</strong> B, Bui-V<strong>in</strong>h Tran P, Osborne MP, Telang<br />
NT. Antisense RNA to the putative tumor-suppressor<br />
gene <strong>DCC</strong> transforms Rat-1 fibroblasts. Oncogene.<br />
1992 Mar;7(3):553-61.<br />
Renault TT, Manon S. <strong>Bax</strong>: Addressed to kill. Biochimie. 2011<br />
Sep;93(9):1379-91.<br />
Shibata D, Reale MA, Lav<strong>in</strong> P, Silverman M, Fearon ER,<br />
Steele G Jr, Jessup JM, Loda M, Summerhayes IC.<br />
The <strong>DCC</strong> prote<strong>in</strong> <strong>and</strong> prognosis <strong>in</strong> <strong>colorectal</strong> cancer.<br />
N Engl J Med. 1996 Dec 5;335(23):1727-32.<br />
Saito M, Yamaguchi A, Goi T, Tsuchiyama T, Nakagawara G,<br />
Urano T, Shiku H, Furukawa K. Expression of <strong>DCC</strong><br />
prote<strong>in</strong> <strong>in</strong> <strong>colorectal</strong> tumors <strong>and</strong> its relationship to<br />
tumor progression <strong>and</strong> metastasis. Oncology.<br />
1999;56(2):134-41.<br />
Tanaka K, Oshimura M, Kikuchi R, Seki M, Hayashi T,<br />
Miyaki M. Suppression of tumorigenicity <strong>in</strong> human<br />
colon carc<strong>in</strong>oma cells by <strong>in</strong>troduction of normal<br />
chromosome 5 or 18. Nature. 1991 Jan<br />
24;349(6307):340-2.<br />
Q<strong>in</strong>gwei Zhou Ph.D Zhongyi Cong Ph.D