images

adiology and biomedical imaging research
• Using imaging to assess new therapies for injured fetuses
and neonates
• Using imaging to assess brain injury in neonates and
infants with severe congenital heart disease
PEDIATRIC RADIOLOGY
John Mackenzie, MD, Chief
NUCLEAR MEDICINE
Miguel Hernandez Pampaloni, MD, PhD, Chief
Research Directions:
Cardiac and vascular applications of clinical SPECT-CT,
PET and PET-CT
• Applications of SPECT-CT for cardiac synchrony
• Dementia imaging with SPECT-CT
• Clinical PET and PET-CT studies of cancer, cardiovascular,
and neurological diseases
• Feasibility of PET and MRI to characterize myocardial
metabolism and flow
• Use of PET to monitor therapy for breast and ovarian
cancers
• Conformal radiation treatment planning with PET-CT
• Imaging structure and function in small animals with CT/
SPECT
• Molecular probe development for SPECT and PET
UCSF DOCUMENTS & MEDIA - MARCO SANCHEZ
Research Directions:
The mission of the Pediatric Radiology section is to improve
the health of children through advanced clinical imaging
and research.
The section studies pediatric disease through the lens of
imaging and is focused on the development of new imaging
technologies.
Several ongoing basic science and clinical studies are
underway with collaborations with MRI physics, pediatric
oncology, pediatric gastroenterology and pediatric surgery.
Examples of research in the Pediatric Radiology section
include:
• Study of novel diffusion weighted imaging (DWI) techniques
to better identify inflammation and monitor treatment
changes in children with inflammatory bowel disease
(ulcerative colitis and Crohn disease).
• Testing and improving motion-resistant MRI with pulse
sequences such as PROPELLER for use in infants and
nonsedated children.
• Examining the strengths and limitations of high-resolution,
3D MRI sequences such as CUBE and SPACE for complex
pediatric diseases in the chest, abdomen and pelvis,
including diseases of the liver, bile ducts, kidneys and
pelvic organs.
• Studying bowel motion (peristalsis) and the changes in
motion that occur in disease using MRI pulse sequences
such as real-time CINE FIESTA.
PEDIATRIC/FETAL RESEARCH INTEREST GROUP
A. James Barkovich, MD, Director
Research Directions:
• Developing new imaging techniques to assess normal
and abnormal development, including MRSI and DTI
• Developing new technology for imaging fetuses and neonates
and adapting state-of-the-art techniques for application
in the developing fetus and infant
• Using imaging techniques to diagnose and study malformations
of the brain
• Using imaging to assess injury in premature and term
neonates
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