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PRIVATE PATENTS AND PUBLIC HEALTH

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TABLE 13 TOP 10 LEADING COMPANIES IN THE GLOBAL CANCER MARKET<br />

BY SALES 239<br />

COMPANY 2014 SALES (IN US$ BILLIONS) 2013 SALES (IN US$ BILLIONS)<br />

Roche 25.15 24.65<br />

Novartis 10.26 9.50<br />

Celgene 7.49 6.34<br />

Johnson & Johnson 3.99 3.36<br />

Bristol-Myers Squibb 3.53 2.94<br />

Lilly 3.39 3.27<br />

Takeda 3.27 3.16<br />

AstraZeneca 2.94 3.09<br />

Merck & Co 2.70 3.05<br />

Amgen 2.06 1.48<br />

Prices of new cancer medication, for example, rise at a higher rate than<br />

public and private spending on health care. This creates challenges even<br />

for health systems and individuals in high-income countries. Cancer drug<br />

prices have doubled in the United States (US) in the last decade from an<br />

average of US$ 5,000 a month to US$ 10,000. 240 The United Kingdom (UK)<br />

is struggling with providing cancer treatment to National Health Service<br />

(NHS) patients. 241<br />

THE IMATINIB (GLIVEC) CASE<br />

Imatinib has helped nearly double the survival rate of people with<br />

chronic myelogenous leukaemia (CML). 242 Originally priced at US$ 30,000<br />

a year in 2001, a group of over 100 physicians from six continents with<br />

expertise in chronic myelogenous leukaemia wrote in the journal Blood<br />

that by 2012 its price had climbed to US$ 92,000 a year after it became a<br />

blockbuster treatment. Generic imatinib, manufactured in India where a<br />

protracted legal case ended in the rejection of imatinib patents, costs<br />

between US$ 2,004–2,112 a year. 243 The authors point out that the research<br />

and development cost has long been earned back by the company and that<br />

the number of patients using imatinib continues to rise, which should<br />

lead to a reduction in price. Instead, since its introduction in the US in<br />

2001, imatinib’s price has nearly tripled. 244<br />

5<br />

THE NEW FRONTIERS: <strong>PATENTS</strong> <strong>AND</strong> TREATMENT FOR CANCER, HEPATITIS C, <strong>AND</strong> OTHER DISEASES<br />

108

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