Nanostructured, electroactive and bioapplicable materials

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8.2. Electroactive, Bioapplicable Materials ............................................................ 221 Appendix A. Stimuli-Responsive Polyphosphazenes as Controlled Drug Delivery Matrix Materials............................................................................................ 223 A.1. Abstract ............................................................................................................ 223 A.2. Introduction ...................................................................................................... 224 A.2.1. Controlled Drug Delivery........................................................................ 224 A.2.2. Polyphosphazene..................................................................................... 226 A.2.2.1. Synthesis of Polyphosphazenes...................................................... 226 A.2.2.2. Applications of Polyphosphazenes in Controlled Drug Delivery.......................................................................................... 228 A.2.3. Stimuli-Responsive Polymers ................................................................. 229 A.3. Proposed Research ........................................................................................... 229 A.3.1. Theoretical Considerations...................................................................... 230 A.3.1.1. Signal ............................................................................................. 231 A.3.1.2. Proposed Intelligent Drug Delivery Systems................................. 231 A.3.2. Experimental ........................................................................................... 235 A.3.2.1. Modification................................................................................... 235 A.3.2.2. Formulation.................................................................................... 235 A.3.2.3. Degradation Study.......................................................................... 236 A.3.2.4. Release Study................................................................................. 236 A.3.2.5. Instrumentation <strong>and</strong> Characterizations........................................... 237 A.4. Ph.D. Thesis Research...................................................................................... 238 A.5. Acknowledgments............................................................................................ 239 x
A.6. References ........................................................................................................ 239 Appendix B Electrochemistry Measurements of Aniline Derivative Modified 8- Hydroxyquinoline Lig<strong>and</strong>s............................................................................ 247 B.1. Experimental .................................................................................................... 247 B.2. Results .............................................................................................................. 247 B.3. Acknowledgments............................................................................................ 248 Vita ....................................................................................................................... 257 xi
Page 1: Nanostructured, Electroactive and B
Page 4 and 5: Dedications This dissertation is de
Page 6 and 7: School of Biomedical Engineering, S
Page 8 and 9: 2.2. Experimental .................
Page 10 and 11: 5.2.2. Treatment of Substrate Surfa
Page 14 and 15: List of Tables Table 2-1. Compositi
Page 16 and 17: Figure 2-9. BJH pore size distribut
Page 18 and 19: xvi pattern of gold nanoparticles i
Page 20 and 21: xviii PANI under culturing conditio
Page 22 and 23: Figure B-8. Cyclic voltammogram (Pt
Page 24: The resultant polyaniline-collagen
Page 27 and 28: Chapter 2 presents a study focused
Page 29 and 30: Chapter 7 is focused on the synthes
Page 31 and 32: surfactant templated method was ext
Page 33 and 34: The porous structure of the silica
Page 35 and 36: Before early 1990s, with a pore or
Page 37 and 38: − Neutral surfactants: the hydrop
Page 39 and 40: The mechanism of nonsurfactant temp
Page 41 and 42: zero in a pore. Structural informat
Page 43 and 44: 1.5.1. Gas Sorption Measurement As
Page 45 and 46: which is usually associated with ca
Page 47 and 48: 16. Iler, R. K. The Chemistry of Si
Page 49 and 50: 52. Sayari, A.; Danumah, C.; Moudra
Page 51 and 52: Figure 1-1. Three structure types p
Page 53 and 54: Figure 1-3. IUPAC classification of
Page 55 and 56: Chapter 2. Mesoporous Sol-Gel Mater
Page 57 and 58: well formed below the isoelectric p
Page 59 and 60: 2.1.2. Nonsurfactant Templates and
Page 61 and 62: since controllable partial removal
Page 63 and 64:
were ground manually into fine powd
Page 65 and 66:
volatile sol-gel reaction byproduct
Page 67 and 68:
After the thermal treatment at 150
Page 69 and 70:
oiling point of benzoin (i.e., 194
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interconnected pores or channels wi
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6. Huo, Q.; Magargolese, D. I.; Cie
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Table 2-1. Composition and pore par
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Weight (%) 100 80 60 40 20 0 0 100
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Weight (%) 100 90 80 70 60 0 100 20
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Weight (%) 100 90 80 70 60 50 40 0
Page 83 and 84:
Figure 2-7. Representative IR spect
Page 85 and 86:
dV/dD Pore Volume (cm 3 g -1 Å -1
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dv/dD, Pore Volume (cm 3 g -1 Å -1
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Net Pore Volume (cm 3 g -1 ) 0.6 0.
Page 91 and 92:
Chapter 3. Synthesis of Mesoporous
Page 93 and 94:
preparation conditions. In general,
Page 95 and 96:
cubic, as well as vesicular structu
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3.2 Experimental The synthesis appr
Page 99 and 100:
3.2.3. Synthesis of Mesoporous Sphe
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fructose is incorporated into the s
Page 103 and 104:
mainly attributed to the monolayer-
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with nonsurfactant templates at dif
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3.4. Conclusions and Remarks In the
Page 109 and 110:
11. Matijević, E.; Gheradi, P. Tra
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41. Polarz, S.; Smarsly, B.; Bronst
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(a) (b) Figure 3-1. Typical SEM ima
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Volume Adsorbed (cm 3 g -1 , STP) 3
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Figure 3-5. Representative TEM imag
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(a) (b) Figure 3-7. Typical SEM ima
Page 121 and 122:
Chapter 4. Synthesis of Mesoporous
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nm, and the reaction reaches the hi
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microemulsion. 39 Martino et al. re
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the colloidal gold sol was combined
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holders with adhesive carbon tape.
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trapped in the gold-silica matrix,
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108 The Barrett-Joyner-Halenda (BJH
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indicative of a well-defined crysta
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(i.e., 2-50 nm). Combining both hig
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19. Hayashi, T.; Tanaka, K.; Haruta
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53. Qi, L.; Ma, J.; Cheng, H.; Zhao
Page 143 and 144:
Figure 4-1. Representative X-ray en
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Pore Volume (cm 3 g -1 A -1 ) 0.06
Page 147 and 148:
(a) (b) 122 Figure 4-5. (a) Represe
Page 149 and 150:
Absorbance Wavelength (nm) Figure 4
Page 151 and 152:
5.1.1. Organic-Inorganic Nanocompos
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128 We are also interested in the p
Page 155 and 156:
mica and graphite, the top layer wa
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mode. Scanning electron microscopy
Page 159 and 160:
Waal’s forces), the agglomeration
Page 161 and 162:
136 A single glass transition tempe
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5.5. Acknowledgments 138 I want to
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30. Dimitrov, A. S.; Nagayama, K. L
Page 167 and 168:
(a) (b) 142 Figure 5-2. Representat
Page 169 and 170:
144 Figure 5-4. Representative AFM
Page 171 and 172:
Figure 5-6. Representative IR spect
Page 173 and 174:
(a) (b) Figure 5-8. Representative
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the possibility of utilizing conduc
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iocompatibility and water solubilit
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emeraldine salt, the unique conduct
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acid (HCl, 37.3%, Fisher), hydrogen
Page 183 and 184:
the surface of polymer coated cultu
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acidic acid aqueous solution showed
Page 187 and 188:
oxidant, indicating the formation o
Page 189 and 190:
complex was synthesized by pre-alig
Page 191 and 192:
8. Epstein, A. J. Springer Ser. Mat
Page 193 and 194:
45. Liu, J.-M.; Yang, S. Chem. Comm
Page 195 and 196:
Figure 6-1. Schematics of biologica
Page 197 and 198:
172 Figure 6-3. UV-Vis absorption s
Page 199 and 200:
Figure 6-5. FT-IR spectra of (a) co
Page 201 and 202:
176 Figure 6-7. UV-Vis absorption s
Page 203 and 204:
(a) (b) 178 Figure 6-9. Comparison
Page 205 and 206:
prepared and purified as substitute
Page 207 and 208:
greatest advantages of organic mate
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een explored as a direct and effect
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if we could fine-tune the carrier t
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NMR (250 MHz, DCCl3) δ (ppm): 8.95
Page 215 and 216:
7.2.4. Instrumentation and Characte
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The absence of the proton from the
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194 The absorbance at 600 nm is the
Page 221 and 222:
L3Al dissociated to free ligand (L)
Page 223 and 224:
198 State and Integrated Circuit Te
Page 225 and 226:
34. Stossel, M.; Staudigel, J.; Ste
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Table 7-1. The UV absorbance at 600
Page 229 and 230:
Figure 7-2. Schematic cross-section
Page 231 and 232:
Figure 7-4. NMR Spectra of ligand 1
Page 233 and 234:
Figure 7-6. FT-IR spectra of (a) li
Page 235 and 236:
Figure 7-8. During air oxidation: 1
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[A] 1.2E-04 1.0E-04 8.0E-05 6.0E-05
Page 239 and 240:
Figure 7-12. Mass spectrum of alumi
Page 241 and 242:
Chapter 8. Concluding Remarks 216 T
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218 In contrast to the conventional
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properties of gold nanoparticles ma
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222 In an effort to obtain new elec
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as sensor units, the biodegradable
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polyanhydrides, 4 polyorthoesters,
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substitution reaction, several hund
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polyphosphazenes. Obtained material
Page 257 and 258:
polyphosphazene network. Studies in
Page 259 and 260:
matrix is readily formed due to the
Page 261 and 262:
236 The delivery system can be made
Page 263 and 264:
phosphazene main chains. Further in
Page 265 and 266:
9. Allcock, H. R. Adv. Mater. 1994,
Page 267 and 268:
Figure A-1. Repeating unit in polyp
Page 269 and 270:
Figure A-3. Applications of materia
Page 271 and 272:
Figure A-5. Preparation of poly(N-i
Page 273 and 274:
B.3. Acknowledgments 248 I am grate
Page 275 and 276:
Figure B-2. Cyclic voltammogram (Hg
Page 277 and 278:
Figure B-4. Cyclic voltammogram (Pt
Page 279 and 280:
Figure B-6. Cyclic voltammogram (Hg
Page 281 and 282:
Figure B-8. Cyclic voltammogram (Pt
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