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Split-read Analysis Paired-end Mapping Analysis

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<strong>Paired</strong>-<strong>end</strong> Clustering<br />

• <strong>Paired</strong>-<strong>end</strong> Clustering<br />

� Nodes equal discordant paired-<strong>end</strong>s<br />

� Edges connect paired-<strong>end</strong>s that support the same SV<br />

� Edge weights indicate level of agreement<br />

� Graph-based SV Clustering Algorithm<br />

� Connected components<br />

� Heuristic maximal clique identification

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