Change Of Diet For children With Autism Suffering - Nutrition and ...

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gastrointestinal tract. Microscopic involvement was observed in 70%, 60% and in 100% of pis in the upper gastrointestinal tract, in the terminal ileum and in the colon respectively, with different histological grade. Mesalazine (8 pts), steroids (2 pts) and 6-mercaptopurine (2 pts) were prescribed according to the histological/clinical score, Casein-free diet and successively glutein-free diet were introduced within the first 3 months by a dietician. A Behavioural Summarized Evaluation (BSE, a score with 29 behavioural items with a degree of frequency validated with a statistical correlation with the Childhood Autism Rating Scale) was used to blindly evaluate the pts at entrance and after 12 months. After 1 year treatment, 80% of pts with severe constipation or diarrhoea had normal stool movements and in 75% an evident reduction of abdominal pain was also observed, The total BSE score showed a global improvement after 12 months that ranged from 10 to 32% (p=0.00388) in all the pts evaluated. When selected symptoms were compared before and after the treatment a reduction of deep anxiety (53%), agitation (35%), mood disturbance (24%), etero-aggressivity (14%), self-aggressivity (13%) as well as an improvement of attention (77%) and sleep (44%) were also observed (p=0.009796). In conclusion, these results proved for the first time a beneficial effect of the combination of drug and dietetic therapy on both bowel and psychiatric symptoms in autism. Registry Numbers: 89-57-6: mesalazine; 50-44-2: 6-mercaptopurine DESCRIPTORS: Major Concepts: Clinical Immunology--Human Medicine, Medical Sciences; Nutrition; Psychiatry--Human Medicine, Medical Sciences; Gastroenterology-- Human Medicine, Medical Sciences Biosystematic Names: Hominidae--Primates, Mammalia, Vertebrata, Chordata, Animalia Organisms: human (Hominidae)--child, preadolescent child, adult, adolescent, female , male Organisms: Parts Etc: colon--digestive system; ileum--digestive system Common Taxonomic Terms: Animals; Chordates; Humans; Mammals; Primates; Vertebrates Diseases: diarrhea--digestive system disease; constipation--digestive system disease; autism--behavioral and mental disorders, complications; autistic enterocolitis--digestive system disease, drug therapy, diet therapy, symptom; lymphoid nodular hyperplasia--blood and lymphatic disease, immune system disease; chronic ileo-colitis--digestive system disease; inflammatory bowel disease {IBD}--digestive system disease, diet therapy Mesh Terms: Diarrhea (MeSH); Constipation (MeSH); Autistic Disorder (MeSH); Inflammatory Bowel Diseases (MeSH) Chemicals & Biochemicals: mesalazine--gastrointestinal-drug; 6mercaptopurine--enzyme inhibitor-drug, immunosuppressant-drug, gastrointestinal-drug, immunologic-drug; steroids--hormone-drug, gastrointestinal-drug Methods & Equipment: gluten-free diet--therapeutic and prophylactic techniques, clinical techniques; casein-free diet--therapeutic and prophylactic techniques, clinical techniques Frequency of gastrointestinal symptoms in children with autistic spectrum disorders and association with family history of autoimmune disease. Valicenti-McDermott Maria; McVicar Kathryn; Rapin Isabelle; Wershil Barry K ; Cohen Herbert; Shinnar Shlomo
Children's Evaluation and Rehabilitation Center, Bronx, New York 10461, USA. rvalicenti@hotmail.com Journal of developmental and behavioral pediatrics - JDBP ( United States ) Apr 2006 , 27 (2 Suppl) pS128-36 , ISSN: 0196-206X--Print Journal Code: 8006933 Contract/Grant No.: K12 NS048856; NS; NINDS NIH HHS United States; RR17672-01; RR; NCRR NIH HHS United States Publishing Model Print Document type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Languages: ENGLISH Main Citation Owner: NLM Record type: MEDLINE; Completed Subfile: INDEX MEDICUS This is a cross-sectional study that compares lifetime prevalence of gastrointestinal (GI) symptoms in children with autistic spectrum disorders (ASDs) and children with typical development and with other developmental disabilities (DDs) and examines the association of GI symptoms with a family history of autoimmune disease. A structured interview was performed in 50 children with ASD and 2 control groups matched for age, sex, and ethnicity-50 with typical development and 50 with other DDs. Seventy-four percent were boys with a mean age of 7.6 years (SD, +/-3.6). A history of GI symptoms was elicited in 70% of children with ASD compared with 28% of children with typical development (p
Page 1 and 2: CHANGE OF DIET FOR CHILDREN WITH AU
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Page 9 and 10: Common Taxonomic Terms: Animals; Ch
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Page 17 and 18: Short report: Autistic gastrointest
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Page 23 and 24: CORRESP. AUTHOR/AFFIL: Levy S.E.: C
Page 25 and 26: also higher regulatory cytokines (I
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Page 33 and 34: team. METHODS: A review of records
Page 35 and 36: Relation of childhood gastrointesti
Page 37 and 38: encephalopathy and a form of autism
Page 39 and 40: children with autism, looking for e
Page 41 and 42: Acta paediatrica (Oslo, Norway - 19

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