Change Of Diet For children With Autism Suffering - Nutrition and ...

(Clostridium clusters I and II) of bacteria than that of healthy children. However,
the non-autistic sibling group had an intermediate level of the C. histolyticum
group, which was not significantly different from either of the other subject
groups. Members of the C. histolyticum group are recognized toxin-producers and
may contribute towards gut dysfunction, with their metabolic products also
exerting systemic effects. Strategies to reduce clostridial population levels
harboured by ASD patients or to improve their gut microflora profile through
dietary modulation may help to alleviate gut disorders common in such patients.
Tags: Female; Male
Descriptors: *Autistic Disorder--microbiology--MI; *Bacteria--isolation and
purification --IP; *Clostridium--isolation and purification--IP; *Feces-microbiology
--MI; *Gastrointestinal Tract--microbiology--MI ; Child; Child,
Preschool; Clostridium histolyticum--isolation and purification--IP; Humans; In
Situ Hybridization, Fluorescence
Record Date Created: 20050913
Record Date Completed: 20051024
Tight junctions, leaky intestines, and pediatric diseases.
Liu Z; Li N; Neu J
International Peace Maternity and Child Health Hospital, Shanghai, China.
Acta paediatrica (Oslo, Norway - 1992) ( Norway ) Apr 2005 , 94 (4) p386-93 ,
ISSN: 0803-5253--Print Journal Code: 9205968
Contract/Grant No.: R01HD38954; HD; NICHD NIH HHS United States
Publishing Model Print
Document type: Journal Article; Research Support, N.I.H., Extramural; Research
Support, U.S. Gov't, P.H.S.; Review
Languages: ENGLISH
Main Citation Owner: NLM
Record type: MEDLINE; Completed
Subfile: INDEX MEDICUS
BACKGROUND: Tight junctions (TJs) represent the major barrier within the
paracellular pathway between intestinal epithelial cells. Disruption of TJs leads to
intestinal hyperpermeability (the so-called "leaky gut") and is implicated in the
pathogenesis of several acute and chronic pediatric disease entities that are likely
to have their origin during infancy. AIM: This review provides an overview of
evidence for the role of TJ breakdown in diseases such as systemic inflammatory
response syndrome (SIRS), inflammatory bowel disease, type 1 diabetes,
allergies, asthma, and autism. CONCLUSION: A better basic understanding of this
structure might lead to prevention or treatment of these diseases using
nutritional or other means. ( 66 Refs.)
Descriptors: *Intercellular Junctions--physiology--PH; *Intestines--cytology--CY ;
Celiac Disease--physiopathology--PP; Child; Diabetes Mellitus, Type 1 -physiopathology--PP;
Epithelial Cells--physiology--PH; Humans; Hypersensitivity-
-physiopathology--PP; Inflammatory Bowel Diseases --physiopathology--PP;
Intestines--physiopathology--PP
Record Date Created: 20050811
Record Date Completed: 20050826
The significance of ileo-colonic lymphoid nodular
hyperplasia in children with autistic spectrum disorder.
Wakefield Andrew J; Ashwood Paul; Limb Kirsten; Anthony Andrew