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Change Of Diet For children With Autism Suffering - Nutrition and ...

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Major Concepts: Behavior; Gastroenterology--Human Medicine, Medical Sciences;<br />

Pediatrics-- Human Medicine, Medical Sciences; Physiology; Psychiatry--Human<br />

Medicine, Medical Sciences<br />

Biosystematic Names: Hominidae--Primates, Mammalia, Vertebrata, Chordata,<br />

Animalia<br />

Organisms: Hominidae (Hominidae)<br />

Common Taxonomic Terms: Animals; Chordates; Humans; Mammals; Primates;<br />

Vertebrates<br />

Miscellaneous Terms: Concept Codes: FOOD RESTRICTION; MENTAL<br />

RETARDATION; SATIATION; THERAPEUTIC INTERVENTION<br />

Response of intestinal mucosa to gluten challenge in<br />

autistic subjects.<br />

McCarthy D M; Coleman M<br />

Lancet ( ENGLAND ) Oct 27 1979 , 2 (8148) p877-8 , ISSN: 0140-6736--Print<br />

Journal Code: 2985213R<br />

Publishing Model Print<br />

Document type: Journal Article<br />

Languages: ENGLISH<br />

Main Citation Owner: NLM<br />

Record type: MEDLINE; Completed<br />

Subfile: AIM; INDEX MEDICUS; Toxbib<br />

Eight autistic patients with steatorrhoea, hypocalciuria, <strong>and</strong> alleged behavioural<br />

improvements on gluten restriction, were fed ordinary diets plus 20 g gluten/day<br />

for 4 weeks. None of the patients had any significant change in body-weight or<br />

bowel habit as a result of gluten challenge, nor were any histological<br />

abnormalities detected on jejunal biopsy. The data suggest that the steatorrhoea<br />

<strong>and</strong> hypocalciuria seen in some autistic subjects cannot be accounted for by the<br />

presence of coeliac disease. Furthermore, these patients should not be confined<br />

to gluten-free diets, unless rigorous behavioural studies demonstrate a<br />

statistically significant improvement in behaviour as a result of the diet, or<br />

deterioration during challenge.<br />

Descriptors: *Autistic Disorder--complications--CO; *Glutens--toxicity--TO;<br />

*Intestinal Mucosa--pathology--PA; *Jejunum--pathology--PA ; Autistic Disorder-<br />

-diet therapy--DH; Autistic Disorder--pathology--PA; Calcium--urine--UR; Calcium<br />

Metabolism Disorders--etiology--ET; Celiac Disease--complications--CO; Celiac<br />

Disease--diagnosis--DI; Child; Glutens --administration <strong>and</strong> dosage--AD; Humans<br />

CAS Registry No.: 7440-70-2 (Calcium); 8002-80-0 (Glutens)<br />

Record Date Created: 19791229<br />

Record Date Completed: 19791229

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