Change Of Diet For children With Autism Suffering - Nutrition and ...

Short report: Autistic gastrointestinal and eating
symptoms treated with secretin: a subtype of autism.
Pallanti Stefano; Lassi Stefano; La Malfa Giampaolo; Campigli Marco; Di Rubbo
Roberto; Paolini Giulia; Cesarali Valentina
Department of Psychiatry, University of Florence, Italy. s.pallanti@agora.it
Clinical practice and epidemiology in mental health - CP & EMH ( England ) Nov
15 2005 , 1 p24 , ISSN: 1745-0179--Electronic Journal Code: 101245735
Publishing Model Electronic
Document type: Journal Article
Languages: ENGLISH
Main Citation Owner: NLM
Other Citation Owner: NLM
Record type: PubMed not MEDLINE
Pervasive Developmental Disorders (PDD) are chronic, lifelong disorders for which
there is as yet no effective cure, and medical management remains a challenge
for clinicians. The current report describes two patients affected by autistic
disorder with associated gastrointestinal symptoms. They received multiple doses
of intravenous secretin for a six-month period and were assessed with several
specific outcome measures to evaluate drug effect. The administration of secretin
led to some significant and lasting improvement in only one case.
Gastroesophageal reflux may contribute to some of the behavioural problems and
explain the effect of secretin since its suppressive effect on gastric secretion is
well known. It is also true that autistic children with gastroesophageal reflux and
a higher IQ could constitute a subtype which responds to secretin administration
and that could be labelled as a "gastrointestinal subtype".
Record Date Created: 20051212
Record Date Completed: 20060123
Date of Electronic Publication: 20051115
Differences between the gut microflora of children with
autistic spectrum disorders and that of healthy children.
Parracho Helena M R T; Bingham Max O; Gibson Glenn R; McCartney Anne L
Food Microbial Sciences Unit, School of Food Biosciences, The University of
Reading, Whiteknights, PO Box 226, Reading RG6 6AP, UK.
Journal of medical microbiology ( England ) Oct 2005 , 54 (Pt 10) p987-91 ,
ISSN: 0022-2615--Print Journal Code: 0224131
Publishing Model Print
Document type: Comparative Study; Journal Article; Research Support, Non-U.S.
Gov't
Languages: ENGLISH
Main Citation Owner: NLM
Record type: MEDLINE; Completed
Subfile: INDEX MEDICUS
Children with autistic spectrum disorders (ASDs) tend to suffer from severe
gastrointestinal problems. Such symptoms may be due to a disruption of the
indigenous gut flora promoting the overgrowth of potentially pathogenic microorganisms.
The faecal flora of patients with ASDs was studied and compared with
those of two control groups (healthy siblings and unrelated healthy children).
Faecal bacterial populations were assessed through the use of a cultureindependent
technique, fluorescence in situ hybridization, using oligonucleotide
probes targeting predominant components of the gut flora. The faecal flora of
ASD patients contained a higher incidence of the Clostridium histolyticum group