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Change Of Diet For children With Autism Suffering - Nutrition and ...

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significantly lower in those on a gluten- <strong>and</strong> casein-free diet, although lymphocyte<br />

populations were not influenced by diet.The data provide further evidence of a<br />

pan-enteric mucosal immunopathology in <strong>children</strong> with regressive autism that is<br />

apparently distinct from other inflammatory bowel diseases.<br />

Descriptors: *Autistic Disorder--pathology--PA; *Inflammatory Bowel Diseases-pathology<br />

--PA; *Intestinal Mucosa--pathology--PA; *Intestine, Small--pathology-<br />

-PA; *Lymphocytes--immunology--IM ; Adolescent; Autistic Disorder-immunology--IM;<br />

Biopsy; Child; Flow Cytometry; Humans; Inflammatory Bowel<br />

Diseases--immunology--IM; Intestinal Mucosa--immunology--IM; Intestine,<br />

Small--immunology--IM; Lymphocyte Subsets--immunology--IM<br />

Record Date Created: 20040319<br />

Record Date Completed: 20041007<br />

Use of complementary <strong>and</strong> alternative treatments for<br />

<strong>children</strong> with autistic spectrum disorders is increasing.<br />

Levy Susan E; Hyman Susan L<br />

Division of Child Development <strong>and</strong> Rehabilitation, Children's Seashore House,<br />

Children's Hospital of Philadelphia, PA, USA.<br />

Pediatric annals ( United States ) Oct 2003 , 32 (10) p685-91 , ISSN: 0090-<br />

4481--Print Journal Code: 0356657<br />

Publishing Model Print<br />

Document type: Journal Article; Research Support, U.S. Gov't, P.H.S.<br />

Languages: ENGLISH<br />

Main Citation Owner: NLM<br />

Record type: MEDLINE; Completed<br />

Subfile: INDEX MEDICUS<br />

Interventions considered to be CAM are in constant flux. New treatments emerge,<br />

older treatments become less popular, <strong>and</strong> the cycle recurs. Data supporting new<br />

treatments should be scrutinized for scientific study design, clinical safety, <strong>and</strong><br />

scientific validity. Many families approach the clinician armed with brochures,<br />

h<strong>and</strong>outs, <strong>and</strong> printouts from Web sites that are dedicated to the care <strong>and</strong><br />

support of parents <strong>and</strong> <strong>children</strong> with ASD. A recent web search using "autism <strong>and</strong><br />

detoxification" resulted in almost 8,000 sites. The Defeat <strong>Autism</strong> Now! (DAN!)<br />

Project arose in 1995 from collaboration of members of the <strong>Autism</strong> Research<br />

Institute. The DAN! Project advocates a specific <strong>and</strong> extensive protocol for<br />

diagnosis <strong>and</strong> treatment <strong>and</strong> can be viewed at http://www.autism.com/ari/#dan.<br />

The scientific validation <strong>and</strong> support for many interventions is incomplete <strong>and</strong><br />

disparate from the recommendation in the American Academy of Pediatrics Policy<br />

Statement. Families should be encouraged to discuss all proposed investigations<br />

or treatments they wish to try with their primary care provider so the practitioner<br />

can serve as the medical home (Sidebar, page 688). The clinician should<br />

communicate <strong>and</strong> collaborate with the family <strong>and</strong> educational professionals to<br />

encourage objective identification of what works. <strong>With</strong> increasing access to health<br />

information <strong>and</strong> societal pressure for families to actively participate in their health<br />

management, continued growth of interest in CAM can be anticipated. Clinicians<br />

must remember that parents may have different beliefs regarding the<br />

effectiveness of treatment <strong>and</strong> different tolerance for treatment risks.<br />

Practitioners must keep avenues of communication open, remain open-minded,<br />

<strong>and</strong> not assume a "don't ask, don't tell" posture in the context of providing a<br />

medical home to the increasing number of <strong>children</strong> diagnosed with autism.<br />

Descriptors: *Autistic Disorder--psychology--PX; *Complementary Therapies-methods--MT;<br />

*Mental Disorders--etiology--ET; *Mental Disorders--therapy--TH ;<br />

Child, Preschool; Complementary Therapies--adverse effects--AE; Evidence-Based<br />

Medicine; Food Habits; Gastrointestinal Agents--therapeutic use--TU; Humans;

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