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Utilizing a different approach, Professor abraham rubinstein is<br />
adapting a nano-delivery system to carry fluorescent biomarkers into<br />
the abdominal regions for the identification of cancer cells. Based on<br />
successful preliminary studies, the system is being developed for testing<br />
during surgery. cancer cells will be visualized with different color<br />
flashing fluorescent markers, enabling the surgeon to either remove or<br />
target them with a cytotoxic drug aimed at cancer cell destruction.<br />
added nano-products are in the pipeline at the school of Pharmacy.<br />
“this is what makes collaboration with the cleveland clinic so exciting,”<br />
explains dr. Galia Blum, who specializes in nano-products that can<br />
be used in improving understanding of the inflammatory processes<br />
associated with cancer, atherosclerosis and arthritis. dr. Blum<br />
Visit www.<strong>afhu</strong>.org/nanomedicine<br />
has focused on using nano-scale probes to investigate atherosclerosis, to view a video about this outstanding<br />
where plaques in the wall of blood vessels can cause narrowing of<br />
new partnership<br />
the arteries and are life-threatening if they rupture. Using specially<br />
designed probes that can be visualized through the use of optical<br />
scanners, scientists have been able to distinguish between stable plaques and those<br />
susceptible to rupture. dr. Blum is working to create nano-scale probes with the aim<br />
of developing a clinical diagnostic tool that can target vulnerable plaques.<br />
inroads are likewise occurring in the area of neurology: dr. sara eyal uses specially<br />
designed nano-particles to target the sites of inflammation associated with epilepsy,<br />
enabling detailed studies of the processes involved. these particles can be<br />
fluorescent and visualized optically via the use of a special microscope during<br />
neurosurgery. they can be instilled with magnetic properties, allowing for non-invasive<br />
viewing through use of an Mri. this vital diagnostic tool has the potential to<br />
incorporate targeted drug therapies.<br />
often, school of Pharmacy experts are members of the Krueger center. “the<br />
cross-fertilization of ideas, combined with israel’s unique entrepreneurial spirit,” states<br />
Professor shy arkin, “helps to make the Hebrew University a superlative partner<br />
for cleveland clinic.”<br />
www.<strong>afhu</strong>.org<br />
<strong>afhu</strong> <strong>news</strong> | 7
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