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04-2018-GL-FINAL

11. Preventing dementia

11. Preventing dementia A team from Loyola University Medical Center found that moderate red wine intake can reduce the risk of developing dementia. A long-term study of data from 19 nations found a statistically significant lower risk of dementia among regular, moderate red wine drinkers in 14 countries. Resveratrol, explained the investigators, is key to this benefit. By reducing the stickiness of blood platelets, it helps keep the blood vessels open and flexible, and this promotes a good supply of blood to the brain. Red and white wines both contain resveratrol, but red wine has more. The skin of red grapes has very high levels of resveratrol. The manufacturing process of red wine, involves prolonged contact with grape skins. The researchers note: "We don't recommend that nondrinkers start drinking. But moderate drinking, if it is truly moderate, can be beneficial." A 2015 study found that a high dose of resveratrol appeared to stabilize a key biomarker for Alzheimer's. The amount needed, however, is far higher than anyone would get from a glass of wine. The participants took a-1 gram (g) supplement by mouth twice a day, equivalent to the amount in 1,000 bottles of wine. 12. Reducing risk of depression A team of researchers from Spain reported in 2013 that drinking wine may reduce the risk of depression. A study of data for around 5,500 men and women aged from 55 to 80 years over a 7-year period showed that those who drank between two and seven glasses of wine each week were less likely to receive a diagnosis of depression, even after taking lifestyle factors into consideration. 13. Protecting from severe sunburn Wine and grape derivatives can help protect the skin from the damaging effects of UV light from the sun, according to scientists from Spain. The team found that when UV rays make contact with human skin, they activate reactive oxygen species (ROS), which oxidize fats, DNA, and other large molecules. These, in turn, stimulate other enzymes that harm skin cells. Wine and grapes contain flavonoids. These inhibit the formation of the ROS in skin cells that are exposed to sunlight. Rather than drinking more wine, however, the researchers suggest incorporating grapes and grape derivatives into sun protection products. 14. Preventing liver disease Modest wine consumption may cut the risk of nonalcoholic fatty liver disease (NAFLD) by half in those who are at risk of the condition, compared with never drinking wine. The finding, published by researchers from the University of California San Diego School of Medicine, is controversial. They note that only moderate consumption will bring benefits, and they 12 April 2018

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