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Nov 2016

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The final Grand Round of <strong>2016</strong><br />

Wednesday 21 September saw the last in<br />

the Eye Doctor’s series of Grand Rounds<br />

for <strong>2016</strong>, held at <strong>Nov</strong>otel Ellerslie. There<br />

was a great turnout of 41 people, a reminder of<br />

the enduring popularity of these Bausch + Lombsponsored<br />

educational talks. Eye Doctor’s are also<br />

celebrating their 10-year anniversary and thanked<br />

the audience for being part of their success story.<br />

From baby rashes to strabismus surgery<br />

Dr Shuan Dai opened the evening with an interesting<br />

case of a six-week old baby presenting with skin<br />

rashes and watering eyes since she was two<br />

weeks old. There was no family history of any eye<br />

conditions. The child was irritable and crying with<br />

a swollen right eye, poor red reflex, and an IOP<br />

of 34mmHg. There was hyphema with no other<br />

causes and this led to the diagnosis of Juvenile<br />

Xanthogranuloma – the most common condition<br />

causing spontaneous hyphema in children.<br />

The condition is characterised by benign cutaneous<br />

histiocyte granulomatous inflammation with 10%<br />

involvement of eye and adnexa. It usually presents in<br />

the first 12 months, and the rash looks like yellowish<br />

slightly raised skin lesions that take a few months to<br />

disappear once treatment begins. It’s a self-limiting<br />

disease though raised intraocular pressure can cause<br />

permanent visual damage unless treated. After two<br />

months using a topical steroid and eye pressure<br />

lowering drops, the IOP came down to 17mmHg.<br />

Signs of amblyopia will need ongoing treatment.<br />

Dr Dai also showed some slides from his ‘working<br />

holiday’ to China, and talked about the new<br />

strabismus surgery techniques he was invited<br />

to present at the ophthalmology conference he<br />

attended in China. He showed excellent surgical<br />

outcome with transposition of superior rectus muscle<br />

to lateral rectus for correcting esotropia in patients<br />

with chronic 6th nerve palsy. The most amazing part<br />

is the restoration of nearly full-range movement<br />

to the eye, he said. Dr Dai showed some video of<br />

pre and post-op patients who had a full range of<br />

movement just a few weeks after surgery.<br />

Scleral thining<br />

Dr Penny McAllum opened with the topic of the<br />

blue/grey tinge to a patient’s eye caused by scleral<br />

thinning. This can be congenital or acquired. If<br />

congenital, it could be Ehlers Danlos Syndrome,<br />

an inherited collagen disorder – ask your patient<br />

to bend back their fingers to see if they have<br />

hyper extendable joints, she said. If their joints are<br />

normal, it could be osteogenesis imperfecta (brittle<br />

bone disease), another collagen defect – check<br />

your patient’s teeth, as people with this condition<br />

often have teeth abnormalities. Another condition<br />

causing the problem could be Marfan syndrome,<br />

a fibrillin disorder resulting in the patient being<br />

unusually tall, with long limbs, fingers and neck,<br />

some heart defects. Lens subluxation is present in<br />

75% due to weak zonules.<br />

Acquired scleral thinning could be the result<br />

of necrotising scleritis/scleromalacia due to<br />

rheumatoid arthritis. The main treatment is oral<br />

Prednisone or other oral immunosuppressant<br />

agents for active disease. Another uncommon<br />

acquired cause is radiation from pterygium<br />

surgery, which can cause scleral melting many<br />

years later. Fortunately, it’s no longer used in New<br />

Zealand. It can also be caused by eye whitening<br />

surgery using mitomycin C, particularly popular<br />

in Korea. Other causes of thin sclera include large<br />

eyes, such as in high myopes or buphthalmos<br />

from congenital glaucoma. A blue or grey scleral<br />

appearance can also result from staining with<br />

some drugs, like tetracyclines, after many years<br />

of regular use. Look for grey, brown or even green<br />

staining of their teeth, skin and nails as well.<br />

Dr McAllum then talked about the interesting<br />

case of a three-year-old Indian boy with yellow<br />

eyes, a sore throat, cough and a fever. He was<br />

diagnosed with jaundice and strep throat – but<br />

what was causing the jaundice? It’s not usual with<br />

strep throat.<br />

She explained that Jaundice is caused by high<br />

levels of bilirubin in the blood stream, a yellow<br />

breakdown product from haemoglobin. There are<br />

three types of jaundice – haemolytic<br />

(increased red blood cell breakdown),<br />

hepatocellular (when the liver is not<br />

functioning properly), and obstructive<br />

(when there is a blockage in the bile<br />

ducts, between liver and intestines),<br />

which is the most common but usually<br />

in adults. Dr McAllum’s patient had<br />

a condition called G6PD deficiency, a<br />

common genetic condition in African,<br />

South Asian and Middle Eastern people,<br />

triggered by some sort of stress on the<br />

body. The patient was in haemolytic<br />

crisis due to his G6PD deficiency,<br />

triggered by the strep throat. It can also<br />

be triggered by aspirin, antimalarial<br />

drugs, some antibiotics and fava<br />

(broad) beans. Once the cause of the<br />

crisis has been removed, the condition<br />

settles on its own.<br />

Dr McAllum said this example served<br />

as a reminder that sometimes you see<br />

things in the eyes that reflect what is<br />

happening elsewhere in the body.<br />

Retinal vasculitis<br />

Retinal vasculitis was the topic<br />

presented by Dr Mark Donaldson.<br />

Clinical signs include perivascular<br />

whitening, haemorrhage in the retina,<br />

a few cells in vitreous, and leakage. Systemic signs<br />

include diabetes, IBS, and smoking.<br />

Dr Donaldson talked us through the case of a fit<br />

asymptomatic 60-year-old woman referred with<br />

retinal haemorrhages. Ultra-wide fluorescein<br />

angiography demonstrated ischemic retina, a<br />

complication that could lead to neovascularisation<br />

and blindness. All possible systemic causes of<br />

vasculitis eliminated the diagnosis defaults<br />

to Eale’s disease with photocoagulation<br />

being recommended. The case succinctly<br />

demonstrated the diagnostic pathways followed in<br />

understanding patients with vasculitis.<br />

Cirrus OCT angiography<br />

Dr Andrew Riley reviewed the Cirrus OCT<br />

angiography, which Eye Doctors purchased after<br />

assessing its potential.<br />

Dr Riley talked about the machines capabilities.<br />

With advancements of live-tracking and faster<br />

Dr Andrew Riley, Stephen Hill, Hue Bullen and Gary Filer<br />

Dr Mark Donaldson, Cindy Tse, Lily Chang, Elkie Wong, and Dr Shuan Dai<br />

acquisition time we can now see the doppler<br />

effect of movement, he said. We actually see the<br />

erythrocyte movement so can map the vessels.<br />

However, he said it does not directly show<br />

leakage. Dr Riley said he is excited about what<br />

this technology provides. Abnormal vessels in<br />

diabetic macular oedema and vein occlusion were<br />

presented and definitions of macular ischaemia<br />

explored. Choroidal neovascularisation from<br />

myopic, trauma and age-related changes can<br />

be identified and mature nets highlighted. The<br />

cases highlighted how OCT angiography has a<br />

bright future not just in diagnosis but also in<br />

improved treatment decisions. This is likely to<br />

reduce considerably the need for fluorescein<br />

angiography, said Dr Riley, adding he envisaged<br />

wider scanning areas with time. Other conditions<br />

are being explored with this technology and optic<br />

nerve vasculature and choroidal circulation are two<br />

where we are just learning, he said. ▀<br />

Bradley Pillay, Dr Penny McCallum and Sonia Swan<br />

Chris Earnshaw and Stuart Campbell<br />

VSP wearables study<br />

Introduced<br />

<strong>Nov</strong>ember 2014<br />

“OptiMed NZ have now sold over 50 Takagi<br />

700GL Slit Lamps”<br />

Slitlamp Microscope<br />

700GL<br />

See your patients’ eyes<br />

in a new light.<br />

VSP Global announced it is<br />

launching a major academic study<br />

and consumer pilot test with the<br />

latest version of the company’s techembedded<br />

eyewear, called Level. The<br />

study is in partnership with University of<br />

Southern California (USC) Center for Body<br />

Computing (CBC),<br />

VSP Global’s innovation lab, The Shop,<br />

debuted an early version of the prototype<br />

in 2015 as Project Genesis— touted as<br />

the first wearable to seamlessly integrate<br />

health-tracking technology into the<br />

temple of an optical frame. A partnership<br />

with USC CBC followed soon after.<br />

“Our partnership with VSP Global will<br />

accelerate research and discovery as to how to<br />

create digital health products and experiences<br />

that will elevate, enhance and expand the lives<br />

of users,” said USC CBC founder and executive<br />

director Dr Leslie Saxon. “This study is the first<br />

of its kind and will provide a crucial roadmap<br />

for validating future products and platforms<br />

and for understanding overall consumer health<br />

engagement.”<br />

The pilot study, launched in September<br />

with USC employees, is being managed by<br />

USC CBC in partnership with USC Roski Eye<br />

Institute. Participants receive a Level frame<br />

and accompanying smartphone app that<br />

allows them to track their activity. The app<br />

also syncs with the VSP Global’s Eyes of Hope<br />

initiative, allowing participants to accrue points<br />

for reaching daily step goals. Once a certain<br />

number of points are achieved, that user<br />

will automatically trigger the donation of a<br />

comprehensive eye exam and a pair of glasses to<br />

someone in need.<br />

VSP’s tech-embedded eyewear Level<br />

“As a community-based not-for-profit, we’re<br />

curious not only about the technology and how<br />

it can benefit the individual utilising it, but<br />

also about the motivations that drive certain<br />

behavior,” said Jay Sales, co-lead of The Shop.<br />

“Connecting Level to our Eyes of Hope initiative<br />

was a perfect way to explore how technology<br />

within a platform as common as eyewear could<br />

increase health and wellness as well as empathy<br />

and opportunity for someone in need.”<br />

Though still in prototype mode, the technology<br />

embedded within the Level frames—including a<br />

gyroscope, accelerometer and magnetometer—<br />

will track a wearer’s steps, calories burned,<br />

and activity time. Users will be able to locate<br />

misplaced frames through the app’s “Find My<br />

Glasses” feature.<br />

It is hoped the study will provide useful feedback<br />

on how individuals interact with the device, which<br />

will inform future strategies for the prototype.<br />

Select eye care providers within the VSP network<br />

will also have an opportunity to test and provide<br />

feedback about the Level experience. ▀<br />

Optional Extras<br />

• Camera Adapter With Yellow Filter<br />

• Adjustable Inclined Eye Piece<br />

• Inclined Eye Piece Adapter<br />

• Yellow Filter<br />

For further information or to order a Takagi Slit Lamp today<br />

Ph: 0800 657 720 info@optimed.co.nz<br />

Craig 0275 657 200 or Robert 0275 657 720<br />

t 012 3456 7890<br />

f 012 3456 7890 e user@yoursite.com<br />

<strong>Nov</strong>ember <strong>2016</strong><br />

NEW ZEALAND OPTICS<br />

9

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