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ages can be affected but it mainly affects chicken older than 3 weeks. In severe form, infected birds have nasal discharge,<br />

rales, coughing, gasping, marked dyspnea and expectoration of blood-stained mucus. Caseous or diphtheric plug or<br />

tracheal core/obstructive haemorrhagic larygotracheitis, while in mild form, birds show unthriftiness, conjunctivitis, swelling<br />

of the infraorbital sinuses with mild tracheitis. Characteristic intranuclear inclusion bodies and syncytia can be observed in<br />

epithelial cells of larynx, trachea and conjunctiva on microscopic examination. Antibodies to ILT virus can be detected by<br />

Virus Neutralisation (VN) tests, AGID reactions, indirect immunofluorescence or ELISA. ELISA is used for flock screening.<br />

Disease can be controlled in endemic areas by use of attenuated live vaccine. New strains have been reported to appear<br />

recently in Australia and ILT is being considered as an ‘‘emerging disease’’.<br />

Multi-drug resistant Salmonella: Emergence of multi drug resistant Salmonella is a strong indication of unregulated<br />

use of antibiotics. As different strains of Salmonella have different antibiotic susceptibilities so careful monitoring should be<br />

done along with antibiotic susceptibility testing. Not only nationwide, but internationally, countries must cooperate to prevent<br />

the relative spread of Salmonella to both neighboring and distant countries.<br />

Avian Gyro Virus infection: Novel virus of family circoviridae, Gyro virus 2 has been detected from chicken flock,<br />

which is a distant relative of Chicken Anaemia Virus (CAV). AGV-2 was mainly isolated from chickens therefore be inferred<br />

that chickens are the main host for AGV-2.<br />

CAV is transmitted both horizontal and vertical from infected breeder hens as CAV replication is regulated by estrogen.<br />

CAV causes a syndrome in young broiler chicks at about 3-6 weeks of age where as in layer chicks from 8-14 weeks of<br />

age. The disease is characterized by aplastic anemia, generalized lymphoid atrophy with a consistent immunosuppression,<br />

depression, retarded growth and increased mortality. On the post-mortem examination atrophy of thymus and bursa and<br />

pale bone marrow. The liver and kidney show discolouration and swelling. Confirmation can be done by isolation of virus liver<br />

of the suspected chickens. Other tests like Virus Neutralization, indirect fluorescent antibody, indirect ELISA and Rt-PCR.<br />

For prevention of disease the parent flocks should be immunized at onset of laying.<br />

Runting Stunting Syndrome (RSS): Runting Stunting Syndrome is a condition affecting broiler chicken and leading to<br />

impaired growth along with poor feed conversion, poor feathering and leg weakness and osteoporosis. The etiology of the<br />

disease is multifactorial and mainly viral entities have been implicated. Femoral head necrosis and infectious proventriculitis<br />

has been seen in the affected birds. Detection and isolation of Reo virus has made it possible etiological agent for the<br />

syndrome. However an infectious bronchitis virus (IBV) -like coronavirus from the intestines of a flock of broiler chicks has<br />

been isolated. Chicken astrovirus has also been isolated from the gut of chickens infected with Runting Stunting Syndrome.<br />

Inactivated vaccine can be given to the broiler breeding birds at about 22-24 weeks of age to prevent the infection in<br />

commercial chicks.<br />

Avian Leukosis (subgroup-J): Avian Leukosis Viruses (ALVs) are a major group of retroviruses associated with neoplastic diseases<br />

like Lymphoid Leukosis (LL) and Myeloid Leukosis (ML) in poultry. The virus spreads horizontally and vertically, and has brought increasingly<br />

severe damage to the poultry industry throughout the world.<br />

References:<br />

Animal and plant health agency (2014). GB emerging threats report. Avian diseases. Avian diseases quarterly report. 18(3): 1-9.<br />

Bagust, T.J. (2013). Poultry health and disease control in developing countries. The role of poultry in human nutrition. FAO. 96.<br />

Causey, D. and Edwards, S.V. (2008). Ecology of avian influenza virus in birds. The Jou infec dis. 197(Supplement 1): S29-S33.<br />

Hafez, H.M. (2003). Emerging and re-emerging diseases in poultry. World Poultry. 19(7): 23-27.<br />

Hagag, I.T., Mansour, S.M., Zhang, Z., Ali, A.A., Ismaiel, E.B.M., Salama, A.A., Cardona, C.J., Collins, J. and Xing, Z. (2015).<br />

Pathogenicity of highly pathogenic avian influenza virus H5N1 in naturally infected poultry in Egypt. PloS one. 10(5): e0120061.<br />

Hauck, R., Gallardo, R.A., Woolcock, P.R. and Shivaprasad, H.L. (2016). A Coronavirus Associated with Runting Stunting Syndrome<br />

in Broiler Chickens. Avian diseases. 60(2): 528-534.<br />

Jhung, M.A., Nelson, D.I. & Centers for Disease Control and Prevention (CDC). (2015). Outbreaks of avian influenza A (H5N2),<br />

(H5N8), and (H5N1) among birds-United States, December 2014–January 2015. MMWR Morb Mortal Wkly Rep. 64(4): 111.<br />

Kwon, Y.M. (2011). Emerging multi-drug resistant Salmonella. Global Health Review.<br />

Pantin-Jackwood, M.J., Stephens, C.B., Bertran, K., Swayne, D.E. and Spackman, E. (2017). The pathogenesis of H7N8 low and highly<br />

pathogenic avian influenza viruses from the United States 2016 outbreak in chickens, turkeys and mallards. PloS one. 12(5): e0177265.<br />

Sary, K., Chénier, S., Gagnon, C.A., Shivaprasad, H.L., Sylvestre, D. and Boulianne, M. (2017). Esophagitis and Pharyngitis Associated<br />

with Avian Infectious Laryngotracheitis in Backyard Chickens: Two Cases. Avian Diseases. 61(2): 255-260.<br />

Sellers, H.S. and Mundt, E. (2015). Chicken Astrovirus Responsible for Runting Stunting Syndrome. U.S. University of Georgia<br />

Research Foundation, Inc. Patent Application 14/612,495.<br />

Yao, S., Tuo, T., Gao, X., Han, C., Li, Y., Gao, Y., Zhang, Y., Liu, C., Qi, X., Gao, H. and Wang, Y. (2016). Avian gyrovirus 2 in poultry,<br />

China, 2015–2016. Emerging microbes & infections. 5(10): e112.<br />

Zhao, J., Zhong, Q., Zhao, Y., Hu, Y.X. and Zhang, G.Z. (2016). Correction: Pathogenicity and Complete Genome Characterization of<br />

Fowl Adenoviruses Isolated from Chickens Associated with Inclusion Body Hepatitis and Hydropericardium Syndrome in China. Plos one.<br />

11(8): e0161744.<br />

102 <strong>November</strong>, <strong>2018</strong>

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