FM DECEMBER 2018 ISSUE - digital edition
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ook review<br />
TERRAINS OF HUMAN<br />
EXPERIENCE<br />
THINK TANK:<br />
FORTY<br />
NEUROSCIENTISTS<br />
EXPLORE THE<br />
BIOLOGICAL<br />
ROOTS OF HUMAN<br />
EXPERIENCE<br />
Edited by David J Lindon<br />
Pp 312<br />
Yale University Press<br />
human brains were not<br />
designed all at once, by a<br />
“Our<br />
genius inventor on a blank sheet<br />
of paper. It is a cobbled-together mess<br />
that nonetheless can perform some very<br />
impressive feats,” observes Dr David J Linden,<br />
introducing the book Think Tank: Forty<br />
Neuroscientists Explore the Biological Roots<br />
of Human Experience, a collection of essays.<br />
The intriguing ways of the human<br />
brain have always been a mystery. This<br />
amazing organ continues to perplex<br />
researchers by simply refusing to unravel. But<br />
in the age of the brain, the world is hungry<br />
to know more about the quirky organ and<br />
the biological basis of human experience.<br />
Most of what is available on the brain is<br />
uninformed or even fraudulent. It’s nothing<br />
but “neurobulshit”, in the words of Dr Linden,<br />
a neuroscientist.<br />
Clearly, that is the reason why Dr Linden<br />
approached the world’s top neuroscientists<br />
with the question: “What idea about brain<br />
function would you most like to explain<br />
to the world?” The result is a collection of<br />
essays that explore various aspects of brain<br />
function.<br />
Contributors with varied expertise survey<br />
the underlying biology of the eternally<br />
fascinating topics of personality, substrates<br />
of aesthetic responses, subconscious drives<br />
for love, sex and food, and psychoactive<br />
drugs. Alongside, they examine the origins of<br />
human individuality, empathy and memory<br />
from different perspectives, such as that<br />
of human behaviour, molecular genetics,<br />
evolutionary biology and comparative<br />
anatomy.<br />
Authors discuss how present concepts<br />
about the working of the brain are getting<br />
refined with progress in neuroscience, even<br />
though we are still quite some distance<br />
from a satisfactory understanding of many<br />
of the processes. Slowly, we come to a new<br />
realisation that several regions of the brain<br />
may be critically involved in mechanisms not<br />
attributed to them hitherto.<br />
The hypothesis of developmental<br />
diaschisis, for instance, now opens the<br />
MOST OF WHAT IS AVAILABLE<br />
ON THE BRAIN IS UNINFORMED<br />
OR EVEN FRAUDULENT. IT’S<br />
NOTHING BUT “NEUROBULSHIT”.<br />
possibility that the treatment of autism could<br />
end up in areas of the brain such as the<br />
cerebellum -- a part of the brain previously<br />
unconnected to cognitive or social functions.<br />
The cerebellum is thought to predict near<br />
future, and in this way, adjust and guide<br />
both movement and thought. A failure of<br />
the cerebellum to predict the near future<br />
could make it hard for babies at risk for<br />
autism to learn properly from the world. This<br />
understanding could change the way we<br />
treat autism. Currently, the most effective<br />
treatment for autism is applied behaviour<br />
analysis. But it works on only half the kids<br />
with autism. Manipulation of brain activity in<br />
the cerebellum may help applied behaviour<br />
analysis work better and help more kids. The<br />
essays are also notable for their brevity and<br />
variety.<br />
<strong>DECEMBER</strong> <strong>2018</strong> / FUTURE MEDICINE / 97