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FM DECEMBER 2018 ISSUE - digital edition

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ook review<br />

TERRAINS OF HUMAN<br />

EXPERIENCE<br />

THINK TANK:<br />

FORTY<br />

NEUROSCIENTISTS<br />

EXPLORE THE<br />

BIOLOGICAL<br />

ROOTS OF HUMAN<br />

EXPERIENCE<br />

Edited by David J Lindon<br />

Pp 312<br />

Yale University Press<br />

human brains were not<br />

designed all at once, by a<br />

“Our<br />

genius inventor on a blank sheet<br />

of paper. It is a cobbled-together mess<br />

that nonetheless can perform some very<br />

impressive feats,” observes Dr David J Linden,<br />

introducing the book Think Tank: Forty<br />

Neuroscientists Explore the Biological Roots<br />

of Human Experience, a collection of essays.<br />

The intriguing ways of the human<br />

brain have always been a mystery. This<br />

amazing organ continues to perplex<br />

researchers by simply refusing to unravel. But<br />

in the age of the brain, the world is hungry<br />

to know more about the quirky organ and<br />

the biological basis of human experience.<br />

Most of what is available on the brain is<br />

uninformed or even fraudulent. It’s nothing<br />

but “neurobulshit”, in the words of Dr Linden,<br />

a neuroscientist.<br />

Clearly, that is the reason why Dr Linden<br />

approached the world’s top neuroscientists<br />

with the question: “What idea about brain<br />

function would you most like to explain<br />

to the world?” The result is a collection of<br />

essays that explore various aspects of brain<br />

function.<br />

Contributors with varied expertise survey<br />

the underlying biology of the eternally<br />

fascinating topics of personality, substrates<br />

of aesthetic responses, subconscious drives<br />

for love, sex and food, and psychoactive<br />

drugs. Alongside, they examine the origins of<br />

human individuality, empathy and memory<br />

from different perspectives, such as that<br />

of human behaviour, molecular genetics,<br />

evolutionary biology and comparative<br />

anatomy.<br />

Authors discuss how present concepts<br />

about the working of the brain are getting<br />

refined with progress in neuroscience, even<br />

though we are still quite some distance<br />

from a satisfactory understanding of many<br />

of the processes. Slowly, we come to a new<br />

realisation that several regions of the brain<br />

may be critically involved in mechanisms not<br />

attributed to them hitherto.<br />

The hypothesis of developmental<br />

diaschisis, for instance, now opens the<br />

MOST OF WHAT IS AVAILABLE<br />

ON THE BRAIN IS UNINFORMED<br />

OR EVEN FRAUDULENT. IT’S<br />

NOTHING BUT “NEUROBULSHIT”.<br />

possibility that the treatment of autism could<br />

end up in areas of the brain such as the<br />

cerebellum -- a part of the brain previously<br />

unconnected to cognitive or social functions.<br />

The cerebellum is thought to predict near<br />

future, and in this way, adjust and guide<br />

both movement and thought. A failure of<br />

the cerebellum to predict the near future<br />

could make it hard for babies at risk for<br />

autism to learn properly from the world. This<br />

understanding could change the way we<br />

treat autism. Currently, the most effective<br />

treatment for autism is applied behaviour<br />

analysis. But it works on only half the kids<br />

with autism. Manipulation of brain activity in<br />

the cerebellum may help applied behaviour<br />

analysis work better and help more kids. The<br />

essays are also notable for their brevity and<br />

variety.<br />

<strong>DECEMBER</strong> <strong>2018</strong> / FUTURE MEDICINE / 97

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