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Warfarin interaction2

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No. Food Possible MOA Potential Effect<br />

Towards INR<br />

17. Royal jelly Unknown<br />

18. Safflower oil Inhibit platelet aggregation<br />

19. Saw palmetto Inhibit cyclooxygenase and<br />

CYPC29<br />

20. Vitamin A (>25000IU/day) Unknown<br />

21. Vitamin B3 (Niacin) Additive anticoagulant effect and<br />

decreased CYP450-mediated<br />

metabolism of warfarin<br />

22. Vitamin C (>1g/day) Unknown<br />

23. Vitamin E (>400 units/day) Pharmacodynamic synergism.<br />

Inhibition the oxidation of<br />

reduced vitamin K, which is<br />

necessary for carboxylation of<br />

vitamin K-dependant clotting<br />

factors for these clotting factors<br />

to be fully functional<br />

24. Vitamin K Antagonised effect of warfarin

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