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Refractive Lens Surgery

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40 D.D. Koch · L.Wang<br />

corneal refractive surgery, the ELP calculated<br />

with the flat postoperative corneal power values<br />

will be artificially low, thereby estimating<br />

that the IOL will sit more anteriorly; this results<br />

in implantation of a lower power IOL<br />

and a hyperopic postoperative refractive error<br />

(Fig. 5.1).<br />

Aramberri [1] proposed a modified IOL<br />

formula, called double-K formula, in which<br />

the pre-refractive surgery corneal power is<br />

used to estimate the ELP and the post-refractive<br />

surgery corneal power is used to calculate<br />

the IOL power, in contrast with the traditional<br />

method in which one corneal power (the<br />

so-called single-K formula) is used for both<br />

calculations. Holladay had previously recognized<br />

this problem when developing the Holladay<br />

2 formula. The magnitude of the error<br />

in predicting ELP depends on the IOL formula<br />

used, the axial length of the eye, and the<br />

amount of refractive correction induced by<br />

the refractive surgery. In general, the ELP-related<br />

IOL prediction errors are the greatest<br />

for the SRK/T formula, followed by Holladay<br />

2, Holladay 1, and Hoffer Q formulas; this error<br />

decreases in long eyes and increases with<br />

increasing amount of refractive correction<br />

[2, 6].<br />

In a previous study, we confirmed the<br />

greater accuracy of the double-K versions of<br />

three third-generation (SRK/T, Holladay 1<br />

and Hoffer Q) and the Holladay 2 fourth-generation<br />

IOL calculation formulas, with decreased<br />

chances of hyperopic surprises [7].<br />

Tables for performing double-K adjustments<br />

on third-generation formulas have been pub-<br />

Fig. 5.1. Most third- and fourthgeneration<br />

IOL formulas predict<br />

the effective lens position (ELP)<br />

using corneal power (a). If the<br />

flattened corneal power after<br />

myopic surgery is used, the<br />

predicted ELP will be anterior<br />

and lower IOL power will be<br />

predicted, resulting in postoperative<br />

hyperopia (b)<br />

lished [2]. The Holladay 2 permits direct entry<br />

of two corneal power values for the double-K<br />

calculation. If the corneal power value<br />

before refractive surgery is unknown, the<br />

“Previous RK, PRK...” box should be checked,<br />

which will instruct the formula to use 44 D as<br />

the default preoperative corneal value. Another<br />

option is to use the Haigis formula,<br />

which does not use the corneal power for ELP<br />

prediction [8].<br />

5.2 Difficulties in Obtaining<br />

Accurate Corneal<br />

<strong>Refractive</strong> Power<br />

Two factors cause the inaccurate estimation<br />

of corneal refractive power:<br />

1. Inaccurate measurement of anterior<br />

corneal curvature by standard keratometry<br />

or CVK. Standard keratometry or simulated<br />

keratometry from CVK measures<br />

only four paracentral points or small regions.<br />

This is insufficient for the post-surgical<br />

cornea, which can have wide ranges<br />

of curvature even within the central 3-mm<br />

region (Fig. 5.2).<br />

2. Inaccurate calculation of corneal refractive<br />

power from the anterior corneal curvature<br />

by using the standardized value for<br />

refractive index of the cornea (1.3375 in<br />

most keratometers and CVK devices).<br />

Based on the assumption that there is a<br />

stable ratio of anterior corneal curvature<br />

to posterior corneal curvature, the standardized<br />

index of refraction has been used

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