PELONews Summer 2020

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<strong>PELONews</strong> New Products & New Partners #3DCellCulture #HTS #spheroids TAGS 3D CoSeedis comprises a family of chips suited for various amounts of 3D constructs. They range from 200 spheroids (3D CoSeedis Chip200) to 880 spheroids per chip (3D CoSeedis Chip880), both in 6 -well plate format, and also include a version for 680 spheroids per chip (3D CoSeedis Chip680) for 24- well plates. Chips can either be purchased in single packages or in bulk. Download your copy of the paper here and contact us for further questions and information. NEW White paper by abc bioplly: How to Revolutionise the Use of 3D Cultures in HTS Our partner abc biopply has released a white paper demonstrating the unprecedented quality of 3D CoSeedis in the production of highly homogenous and uniform spheroids for the use in high-throughput and highcontent screening applications. The paper was done in collaboration with Union Biometrica, Inc. (USA) and shows how 3D CoSeedis can be used as a manufacturing tool to produce large quantities of homogenous and uniform 3D spheroids in a HTS/HCScompatible 384-well format. The 3D CoSeedis platform thereby not only sets new standards in highvolume production of 3D spheroids but it also helps to substantially increase screening efficiency. It’s based on a 24-well plate format for aggregation, growth and harvesting and the resulting spheroid suspension is used to seed 384-well plates with individual spheroids using Union Biometrica’s large particle sorter. The resulting 384-well plates contain viable and uniform spheroids in more than 98% of all the wells and show minimal size variability from one plate to another. 3D CoSeedis thereby helps to decrease screening failure rates and consequently increases overall screening efficiency NEW Media & New Partner for MSCs Cell culture is a critical component of research, development and production in the life sciences. Cell culture media in particular, has a significant impact on the efficacy and sensitivity control of the cell culture microenvironment. PELOBiotech is strenghtening its leading position in the field of MSCs & GMP: We added two media for MSCs to our portfolio called CellCor, a serum free chemically defined media composed of over 200 known compounds. Through 10 years of tenacious research, producer Xcell Therapeutics , South Korea, developed CellCor SFD MSC and CellCor CD MSC products, which provide superior performance with the upmost focus safety and quality, assured by strict adherence to regulated standards following good manufacturing practices. CellCor does not contain any animal nor plant derived components, they are hPL free, and Exosome free, available in R&D and GMP quality.
New Products Myell: Get clear pictures of Live Cell Imaging Myell series is a polymer "superthin" film "which is a novel alternative tool for cover glass" and offers a new method to make sample for microscope observation. By using with Myell series, the samples are prevented from vibrating. This makes us to get clear picturesin Live Cell Imaging. *Myell series are NOT sterilized Myell A/S: Prevent samples from vibrating> When observing cells such as floating cellsor yeast, dropping cell suspension on a glass bottom dish is general method. However,this method has a problem that the picture becomes blurry because the cells vibrate due to their brownian motion. By wrapping with Myell A/S, the samples on aslide grass are prevented from vibrating. This makes usto get clear pictures. Also, pictures hardly blurry even if some droplets are added on samples wrapped with Myell A/S. Please click Here! https://fnkprddata.blob.core.windows.net/domestic/f-img/Image/TUN% 20_myell_wrapping_54sec.mp4 Product Name Code Size Poro us Myell A MYLL-A3 3 sheets - Myell S MYLL-S10 10 sheets - Material Polylactic acid Myell D MYLC-D10 10 sheets - CYTOP ® Myell P MYLL-P4 4 sheets 6µm Polylactic acid Enjoy our comprehensi ve PELOBiotech -Productlists MSCs, Tools & Media: www.yumpu.c om/en/ embed/view/ iApHInxFeXgG Vk2N Human Cells: www.yumpu. com/en/ embed/view/ Tt8iOdyNeG6 RhD0I Animal Cells: www.yumpu. com/en/ embed/view/ KMxQalvUim o4SetV Papers, Papers, Papers A microfluidic model of human brain (μHuB) for assessment of BBB Microfluidic cellular models, commonly referred to as “organs-on-chips,” continue to advance the field of bioengineering via the development of accurate and higher throughput models, captivating the essence of living human organs. SynBBB in vitro blood brain barrier (BBB) model allows visualization of cellular interactions and barrier functionality in real time. Evaluate and quantitate permeability of therapeutics and small molecules across the endothelium of the BBB in real-time. Unlike BBB models that are membrane-based and arranged in top to bottom architecture (i.e., Transwell), small molecule transport can be visualized, accessed and quantified in real-time using the SynBBB model due to its side-by-side architecture. https://doi.org/10.1002/btm2.10126 by Tyler D. Brown et al
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