Status and Future Directions of the - US Environmental Protection ...

87
CAS # 1990 Manufacturer
STEPAN CHEMICAL COMPANY
70084-98-9 UNION CAMP CORPORATION
76
1998
Manu.
2002
Manu.
Status and Future Directions of the HPV Challenge Program – Final Draft – 10/19/04
Trade
Association
70693-50-4 CIBA-GEIGY CORPORATION TEXTILE PRODUCTS * * ACC, API
70851-08-0 RHONE POULENC INCORPORATED
71077-05-9 TEXACO CHEMICAL COMPANY ACC, API, SOCMA
72162-28-8 GE PLASTICS * * API
73665-18-6 KOPPER COMPANY INCORPORATED *
83864-02-2 EI DUPONT DE NEMOURS & CO INC * ACC
84501-86-0 WERNER G SMITH INC * *
90640-80-5 KOPPER COMPANY INCORPORATED *
90640-86-1 KOPPER COMPANY INCORPORATED * *
119345-02-7 DOW CHEMICAL USA ACC, API, SOCMA
125997-20-8 GREAT LAKES CHEMICAL CORPORATION - RESEA
------------------------------------------------------------------------------------
The The table table reveals reveals that for that the for 330 the orphan 330 orphan chemicals, chemicals, HPV there Challenge are: 151 Program cases where Unsponsored a company Chemicals,”
member from the ACC trade association could have sponsored a chemical; 83 cases where a
there company are: 151 cases member where from a company the API member trade association from could outlines have EPA’s sponsored initial thinking a chemical; for obtaining and 91hazard
the ACC cases trade where association a company could member have sponsored from the a SOCMA screening-level trade association data for could the have 330 orphan sponsored chemicals a
chemical (note that the API company list was not a complete list of members).
chemical; 83 cases where a company member from and making the data publicly available in the HPV
the API The trade figure association below, which could is have a flowchart sponsored on a the following Information page entitled System. “Preliminary (HPVIS is Strategy a data-searchable for
Addressing HPV Challenge Program Unsponsored Chemicals,” outlines EPA’s initial thinking for
chemical; obtaining and 91 hazard cases where screening-level a company data member for the from 330 orphan application chemicals for HPV and Challenge making Program the data data that
the SOCMA publicly available trade association in the HPV could Information have sponsored System. is (HPVIS discussed is a later data-searchable in this report.) application EPA continues for to
HPV Challenge Program data that is discussed later in this report.) EPA continues to recognize
a chemical the HPV (note Challenge that the API Program company as a list dynamic was not and a fluid recognize program, the and HPV any Challenge strategy Program for addressing as a dynamic
complete orphan list chemicals of members). must be flexible to accommodate and changing fluid program, Program and circumstances any strategy for and addressing EPA
and stakeholder needs.
orphan chemicals must be flexible to accommodate
The figure below, which is a flowchart on the following
page entitled “Preliminary Strategy for Addressing
changing Program circumstances and EPA and
stakeholder needs.
EPA’s High Production Volume Challenge Program
Approximately 241 meet the HPV
Challenge Program “No Longer
HPV” criterion and will not be a
direct focus of follow-up work
under the HPV Challenge
Program at this time.
8.
ITC-coordinated TSCA
8(d) Unpublished
Health and Safety Data
Rule and TSCA 8(a)
PAIR Rule to gather
exposure data for
future test rule findings.
9.
Are studies
available/submitted to
EPA adequate to meet
SIDS endpoints?
Yes
Status and Future Directions
Preliminary Strategy for Addressing HPV
Challenge Program Unsponsored Chemicals
Make data publicly
available in HPVIS.
3.
Yes
Does the
chemical meet
“No Longer HPV”
criterion?
5.
Yes
Can test
rule exposure-based
findings be made with
currently available
information
No
10.
Can test rule
exposure-based
findings be made with
PAIR and/or other
currently available
information?
No
Yes
11.
Propose and finalize Third HPV Test
Rule for Chemicals for which findings
can be made. Consider risk-based
findings for chemicals where needed.
571 Unsponsponsored
Chemicals based on 1990 HPV
Challenge Programming List
No
2. Yes
Is chemical
included in First
HPV Test
Rule?
No
No
~330 orphan
chemicals
12.
Seek other data
development
mechanism for
chemicals with
continuing hazard
and fate data gaps.
1.
EPA and others may engage
in activities to secure
additional HPV sponsors.
4.
Finalize the First HPV Test
Rule. Identify SIDS endpoint
studies not addressed in the
First HPV Test Rule.
6.
Yes
Are there any
publicity available
studies that are adequate
to fulfill HPV Challenge
Program needs?
No
7.
Propose and finalize
Second HPV Test Rule
addressing inadequate
studies for specific
endpoints. Also include
in this test ruls studies
that address endpoints
left uncovered in the
First HPV Test Rule for
which there are
inadquate studies.
88