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Org. age Ohio . 711 - The Ohio State University

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Academic Divisions, 2005-06<br />

Division of Medicinal Chemistry and Pharmacognosy<br />

Li, Pui-Kai Associate Professor and Interim Chair<br />

Brueggemeier, Robert W. Professor and Dean<br />

Carcache de-Blanco, Esperanza Assistant Professor (joint, Pharmacy<br />

Practice and Administration)<br />

Chen, Ching-Shih Professor<br />

Curley, Robert W. Professor<br />

Kinghorn, A Douglas Professor and Jack L. Beal Chair<br />

Li, Chenglong Assistant Professor<br />

Tjarks, Werner Assistant Professor<br />

Werbovetz, Karl A. Assistant Professor<br />

Whetstone, Jennifer L. Visiting Assistant Professor<br />

Cassady, John M. Emeritus Professor and Dean<br />

Doskotch, Raymond Professor Emeritus<br />

Jagadeesh, Jogikal Professor Emeritus<br />

Olson, Carter Professor Emeritus<br />

Robertson, Larry Professor Emeritus<br />

Soloway, Albert Emeritus Professor and Dean<br />

Pui-Kai (Tom) Li<br />

<strong>The</strong> Division of Medicinal Chemistry and Pharmacognosy is composed of faculty members with diversified<br />

research interests representing synthetic organic, natural products, and biological chemistry. <strong>The</strong> research areas<br />

focus on the interdisciplinary application of chemical and biochemical principles to the identification and<br />

development of therapeutic <strong>age</strong>nts. Research in medicinal chemistry emphasizes drug design and includes the<br />

synthesis of organic medicinal products, elucidation of the biochemistry of medicinal <strong>age</strong>nts, examination of<br />

the relationship of chemical structure to biological activity, qualitative and quantitative analysis of drugs and<br />

related products, and application of computational<br />

chemistry to drug design. Research in pharmacognosy<br />

emphasizes drug discovery and encompasses the isolation<br />

and structure determination of pharmacologically active<br />

natural products from plants and microbes, studies on<br />

the structure and biochemistry of biological products,<br />

examination of the biosynthesis of natural products, and<br />

evaluation of the biochemical effects of these active<br />

constituents.<br />

Faculty productivity is reflected in scholarly activities<br />

and graduate education, both of which continue at an<br />

accelerated pace. Graduate programs are organized<br />

around faculty expertise into three disciplines -<br />

medicinal chemistry, biomedical and natural products.<br />

Currently, there are 47 graduate students in the division. Three students from the <strong>Ohio</strong><br />

<strong>State</strong> Biochemistry Program and three students from Electrical Engineering are directed<br />

by Medicinal Chemistry faculty. <strong>The</strong>se students are involved in medicinal chemistry<br />

research, natural products chemistry, biosynthesis and pharmacognosy research.<br />

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