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Lishan Su, PhD Investiture Program

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LISHAN SU, PHD<br />

of North Carolina-Chapel Hill.<br />

<strong>Lishan</strong> <strong>Su</strong>, <strong>PhD</strong> grew up in Qingdao,<br />

China, and received his BS in Microbiology<br />

from Shandong University, <strong>PhD</strong> in Virology<br />

from Harvard University, and did postdoctoral<br />

training in Immunology at Stanford<br />

University. Dr. <strong>Su</strong> then worked as a<br />

research scientist in a biotech company,<br />

focusing on HIV pathogenesis and testing<br />

blood stem cell-based HIV-1 gene therapy<br />

in HIV-infected patients. From 1996 to<br />

2021, he was a faculty member in the<br />

Lineberger Comprehensive Cancer Center<br />

and Professor in the Department of<br />

Microbiology & Immunology at University<br />

For over two decades, Dr. <strong>Su</strong> has focused on studying several critical areas<br />

of immuno-pathology of human chronic virus infections, particularly on<br />

elucidating how HIV causes AIDS-related diseases. The <strong>Su</strong> laboratory<br />

studies how HIV-1 and HBV interact with human immune cells to cause<br />

diseases. His research team has focused on the plasmacytoid dendritic cell<br />

(pDC)-interferon axis in the pathogenesis and therapy of chronic HIV<br />

infection and Disease-Associated Macrophages (DAM)-hepatic stellate cells<br />

in HBV-induced liver diseases in humanized mice and in patients. The team<br />

has also started investigation of the pathways in tumor microenvironments<br />

(TME) and in cancer immune therapy. After joining The Institute of Human<br />

Virology at UMSOM, Dr. <strong>Su</strong> continued his research program to use HIV and<br />

HBV viruses as probes to dissect human immunity and inflammatory<br />

diseases, and to develop antibody and cell-based drugs targeting novel<br />

immune cells and signaling pathways to treat human inflammatory diseases<br />

including virus infection and cancer. He has also trained over 40 postdoc/<br />

visiting scholars and 20 graduate students from 8 different countries.<br />

Dr. <strong>Su</strong> has served on grant review committees for US/European and Chinese<br />

funding agencies for over 20 years, and as associate editor or on editorial<br />

boards of several journals. For the past 20 years, Dr. <strong>Su</strong> has also interacted<br />

with US and international institutions, including providing advice and to<br />

evaluate progress to biomedical research institutes and centers. He has also<br />

received several awards over the years, including election as a Fellow of the<br />

American Association for the Advancement of Science in 2012, and the<br />

Charles Gordon Smith Endowed Professorship for HIV Research in 2021.

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