TRISOMY 8 MOSAICISM: CELL CYCLE KINETICS AND ...

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Table 3. Trisomy 8 Cells in G-banded Metaphases vs. FISH Interphases Tissue Metaphase Interphase* Chi Squared Cord Blood 55% 62% p
For each tissue the metaphase and interphase percentages of trisomy 8 cells were statistically compared by the Chi-squared goodness of fit test (Table 3). The trisomy 8 cell percentages of the cord blood and amnion were found not to be significantly different, while the transformed blood, peripheral blood, umbilical cord, and chorion were found to have a significant difference of at least p
Page 1 and 2: TRISOMY 8 MOSAICISM: CELL CYCLE KIN
Page 3 and 4: TABLE OF CONTENTS iii Page Abstract
Page 5 and 6: Trisomy 8 INTRODUCTION Trisomy 8 (T
Page 7 and 8: proliferates and thus mosaicism res
Page 9 and 10: Prenatal Testing Prenatal testing i
Page 11 and 12: DNA undergoing synthesis. Once a sa
Page 13 and 14: centrifugation, aspiration, and fix
Page 15 and 16: insed with water and allowed to air
Page 17 and 18: fixative, and the centrifugation an
Page 19 and 20: FISH slide preparation Day 1 Slides
Page 21 and 22: Case Report RESULTS Amniocentesis,
Page 23 and 24: Figure 2 Trisomy 8 [46, XY, +8] Kar
Page 25 and 26: When comparing embryonic tissues, c
Page 27 and 28: Figure 4 FISH Trisomy 8 [46, XY, +8
Page 29: There was a notable difference betw
Page 33 and 34: Figure 6 Second Division - Cell Cyc
Page 35 and 36: Table 4. Division Rates for Normal
Page 37 and 38: Origin of Trisomy 8 cells DISCUSSIO
Page 39 and 40: original finding of La Marche in th
Page 41 and 42: Pallister Killian patients with the
Page 43 and 44: BIBLIOGRAPHY Berry AC, Mutton DE, a
Page 45: Thornberg Reeser SL and Wenger SL.

TRISOMY 8 MOSAICISM: CELL CYCLE KINETICS AND ...

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