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46 EHMTIC20I2 European Headache and Migraine Trust International Congress Poster Programme contInued P71 Magnesium and memantine do not inhibit nociceptive neuronal activity in the trigeminocervical complex of the rat Hoffmann, J.; Park, J.W.; Storer, R.J.; Goadsby, P.J. Headache Group - Department of Neurology, University of California San Francisco, United States P72 Role of TRPV-1 in CGRP-mediated trigeminal sensitization Chatchaisak, D. 1 ; Chetsawang, B. 2 ; le Grand, S.M. 3 ; Govitrapong, P. 2 ; Srikiatkhachorn, A. 4 1Research Center for Neuroscience, Institute of Molecular Biosciences, Mahidol Universit, Salaya, Nakhonpathom 73170, Thailand; 2aResearch Center for Neuroscience, Institute of Molecular Biosciences, Mahidol Universit, Salaya, Nakhonpathom 73170, Thailand; 3Department of Pathology, Faculty of Medicine, Chulalongkorn University, Thailand; 4Deaprtment of Physiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand P73 Dynamic balance decreased in postdromal migraineurs compared to non migraine controls Moore, M.T.; Feuerherd, R. Northern Michigan University, United States P74 Neurocognitive function declines are reversible following migraine headache in college students Moore, M.T. 1 ; Covassin, T. 2 ; Pfeiffer, K.A. 2 ; Norris, R.E. 2 ; Jensen, R.L. 1 ; Branta, C.F. 2 1 2 Northern Michigan University, United States; Michigan State University, United States P75 Sustained pain relief with dihydroergotamine in migraine is potentially due to persistent binding to 5-HT1B and 5-HT1D receptors Kori, S. 1 ; Zhang, J. 1 ; Kellerman, D. 1 ; Armer, T. 1 ; Goadsby, P. 2 1 2 MAP Pharmaceuticals, United States; Dept of Neurology, UCSF, United States P76 Modulation of trigeminovascular activity by leptin: a novel antinociceptive mechanism? Martins-Oliveira, M.; Hoffmann, J.; Akerman, S.; Goadsby, P.J. Headache Group, Department of Neurology, University of California San Francisco, San Francisco CA, United States P77 Investigation of 5-HT2B receptor induced dural plasma protein extravasation in a mouse migraine model Hunfeld, A.; Segelcke, D.; Andriske, M.; Paris, F.; Zhu, X.; Lübbert, H. Ruhr-Universität Bochum, Germany P78 Activation of 5-HT2B-receptors leads to increased vasodilation in mouse dura mater blood vessels Segelcke, D.; Schulte, C.; Kremser, M.; Hunfeld, A.; Lübbert, H. Ruhr University Bochum, LS Animal Physiology, Germany P79 Monitoring cortical neuronal activity and spreading depression in freely behaving familial hemiplegic migraine Cacna1a R192q knockin mice Houben, T. 1 ; Shyti, R. 2 ; Dees, q. 2 ; van Berloo, S. 3 ; de Groote, L. 1 ; Terwindt, G.M. 1 ; Ferrari, M.D. 1 ; Tolner, E.A. 1 ; van den Maagdenberg, A.M. 2 1 2 Department of Neurology, Leiden University Medical Center, Leiden, Netherlands; Department of Human Genetics, Leiden University Medical Center, Leiden, Netherlands; 3Instrument Development Department, Leiden University Medical Center, Leiden, Netherlands P81 Characterization of a novel model for chronic migraine. Pradhan, A.; McGuire, B.; Charles, A. University of California, Los Angeles, United States P82 The effects of botulinum toxin type A on the trigeminal TRPV1 containing neurons innervating the dura mater of rat Shimizu, T. 1 ; Shibata, M. 1 ; Toriumi, H. 2 ; Iwashita, T. 2 ; Funakubo, M. 2 ; Sato, H. 2 ; Kuroi, T. 2 ; Ebine, T. 2 ; Koizumi, K. 2 ; Suzuki, N. 2 1 2 Keio University, School of Medicine, Japan; Keio University, School of Medicine,, Japan
EHMTIC20I2 European Headache and Migraine Trust International Congress P83 Differential cellular localization of antioxidant enzymes in the trigeminal ganglion Shibata, M. 1 ; Sato, H. 1 ; Shimizu, T. 1 ; Shibata, S. 2 ; Toriumi, H. 1 ; Kuroi, T. 1 ; Ebine, T. 1 ; Iwashita, T. 1 ; Funakubo, M. 1 ; Akazawa, C. 3 ; Wajima, K. 4 ; Nakagawa, T. 4 ; Okano, H. 2 ; Suzuki, N. 5 1 Department of Neurology, School of Medicine, Keio University, Japan; 2 Department of Physiology, School of Medicine, Keio University, Japan; 3 Department of Biochemistry and Biophysics, Graduate School of Health and Sciences, Tokyo Medical and Dental University, Japan; 4 Department of Dentistry and Oral Surgery, School of Medicine, Keio University, Japan; 5 Department of Neurology, School of Medicine, Keio University, United Kingdom P84 Influence of ovarian hormones on occurrence of cortical spreading depression and its suppression of by L-kynurenine in rat Chauvel, V.; Multon, S.; Schoenen, J. GIGA Neurosciences, Belgium P85 Corticosterone enhances CSD susceptibility via glucocorticoid receptor activation in familial hemiplegic migraine 1 Cacna1a knock-in mice Shyti, R. 1 ; Eikermann-Haerter, K. 2 ; Meijer, O.C. 3 ; van Heiningen, S.H. 1 ; De Groote, L. 4 ; Ferrari, M.D. 5 ; Ayata, C. 2 ; van den Maagdenberg, A.M.J. 6 ; Tolner, E.A. 7 1 2 Dept of Human Genetics, Leiden Univ. Medical Center, Leiden, Netherlands; Neurovascular Research Laboratory, Dept of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, United States; 3Dept of Endocrinology, Leiden Univ. Medical Center, Leiden, Netherlands; 4Dept of Neurology, Leiden Univ. Medical Center, Leiden, Netherlands; 5Dept of Neurology,, Netherlands; 6Dept of Human Genetics, Leiden Univ. Medical Center, Leiden, Netherlands; 7Dept Neurology, Leiden Univ. Medical Center, Leiden, Netherlands P86 Repeated methylene blue administration produces analgesia in experimental pain Dondas, A. 1 ; Luca, A. 1 ; Alexa, T. 1 ; Grigoras, V.A. 2 ; Mungiu, O.C. 1 ; Bohotin, C.R. 1 1Centre for the Study and Therapy of Pain, University of Medicine and Pharmacy, Grigore. T. Popa, Romania, Romania; 2Department of Neurology, Rehabilitation Hospital, University of Medicine and Pharmacy, Grigore. T. Popa, Romania, Romania P87 Chronic cobalt exposure modifies nociception and orofacial inflammatory pain Alexa, T. 1 ; Dondas, A. 1 ; Luca, A. 1 ; Grigoras, V.A. 2 ; Mungiu, O.C. 3 ; Bohotin, C.R. 3 1 2 Centre for the Study and Therapy of Pain, University of Medicine and Pharmacy “Grigore T Popa” Iasi, Romania; Department of Neurology, Rehabilitation Hospital, University of Medicine and Pharmacy “Grigore T Popa” Iasi, Romania; 3Centre for the Study and Therapy of Pain, Department of Oncology, University of Medicine and Pharmacy “Grigore T Popa” Iasi, Romania P88 Involvement of TRPA1 receptors in meningeal blood flow induced by formation of nitroxyl (NO-/HNO) Dux, M. 1 ; Eberhardt, M. 2 ; Filipovic, M.R. 3 ; DeCol, R. 2 ; Messlinger, K. 2 1 2 Department of Physiology, University of Szeged, Hungary; Institute of Physiology & Pathophysiology, University of Erlangen- Nuernberg, Germany; 3Department of Chemistry and Pharmacy, University of Erlangen-Nuernberg, United Kingdom P89 Differentiation of nerve fibers storing CGRP and CGRP receptors in the peripheral trigeminovascular system Eftekhari, S.; Warfvinge, K.; W. Blixt, F.; Edvinsson, L Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, Lund, Sweden., Sweden P90 Glyceryl trinitrate has opposite effects on different experimental models of pain Grigoraay, V.A. 1 ; Luca, A. 2 ; DondaÅŸ, A. 2 ; Alexa, T. 2 ; Mungiu, O.C. 2 ; Bohotin, C.R. 2 1 2 Department of Neurology, Recovery Hospital, Grigore T Popa University of Medicine and Pharmacy Iasi, Romania; Centre for the Study and Therapy of Pain, University of Medicine and Pharmacy, Grigore T Popa University, Iasi, Romania P91 CGRP and CGRP receptors in human and rhesus monkey cerebellum Eftekhari, S. 1 ; Salvatore, C.A. 2 ; Connolly, B.M. 3 ; O’Malley, S. 3 ; Miller, P.J. 3 ; Zeng, Z. 3 ; Edvinsson, L. 4 1 2 Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, Lund, Sweden; Department of Pain and Migraine Research, West Point, PA, United States; 3Department of Imaging, Merck Research Laboratories, West Point, PA, United States; 4Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, Lund, Sweden P92 Measurements of 17β-estradiol levels in mice for migraine research Chan, K. 1 ; Labruijere, S. 1 ; Garrelds, I. 1 ; Danser, A. 1 ; Villalón, C. 2 ; MaassenVanDenBrink, A. 1 1 2 Erasmus Medical Center, Netherlands; Cinvestav Coapa, Czda, Mexico 47
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