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General embryological information service - HPS Repository

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.<br />

Nicolson, Rasmussen, De Petrocellis) ; V. Neural differentiation (Frank,<br />

Macagno)<br />

The title of this book should have contained the word "development". It<br />

is based on a symposium held in Woods Hole, Mass. in September 1976 and is<br />

one of those few symposium volumes that are sure to leave a lasting mark.<br />

All contributions are short to medium-length reviews of very recent work in<br />

a limited area, but they were all obviously prepared with great care and<br />

are well integrated by cross-referencing. A great variety of mostly vertebrate<br />

cells and tissues pass in review, on which the most modern methods<br />

are brought to bear<br />

The book is produced with exemplary care and illustrated, among other<br />

things, with a host of beautiful half-tones.<br />

85.<br />

R.A.LERNER and D.BERGSMA, eds. 1978. THE MOLECULAR BASIS OF CELL-CELL INTER-<br />

ACTION<br />

Liss, New York. Birth Defects: Original Article Series, vol.14, 2.<br />

XVIII, 566 pp., 255 figs., 53 tabs., subject index. $ 58.00<br />

Contents (abridged): I. Cell-surface membrane complex (3 papers); II. Organelles<br />

and supraraolecular assemblies (4); III. Cell surface proteins (8)<br />

IV. Cell-cell interactions (9); V. Communicating cell systems (10); VI.<br />

Cell patterning (2)<br />

More than one third of the 36 papers in this conference report are of<br />

direct interest to developmental biologists. This reflects the fact that cell<br />

interactions (why is the ugly phrase "cell-cell interaction" increasingly<br />

used?) are often best studied in developing systems.<br />

The conference took place some time during 1977 in La Jolla, CA and the<br />

large majority of contributors are Americans. The papers vary widely in<br />

scope; most can be characterised as progress reports. Many developmental<br />

biologists will also be interested in the "non-developmental" papers, particularly<br />

those dealing with lymphocytes and histocompatibility antigens: the<br />

latter are increasingly suspected to have much more profound functions than<br />

those expressed in graft rejection alone.<br />

The papers of primary interest to our readers are in sections IV-VI. The<br />

last section is made up by two brief reviews by Bryant (epimorphic fields)<br />

and Wolpert (chick limb development) . Section V has no less than six papers<br />

on cellular slime moulds, some of them unconnected with the theme of the conference<br />

(genetics and gene expression) . Section IV has a long paper by Boyse<br />

and Cantor on immunogenetical aspects of biological communication, which<br />

contains most interesting speculations. Other papers are on the T-locus of<br />

the mouse, on "cell-adhesion molecules" in chick embryos, and on fertilisation<br />

in mammals and sea urchins.<br />

The volume is well produced and illustrated.<br />

86.<br />

B.I. LORD, C.S.POTTEN and R.J.COLE, eds. 1978. STEM CELLS AND TISSUE HOMEO-<br />

STASIS<br />

Cambridge Univ. Press, Cambridge, etc. Symp. Brit. Soc. Cell Biol. no. 2.<br />

VIII, 368 pp., 73 figs., 20 tabs., combined taxonomic and subject index.<br />

£ 18.50<br />

As Holtzer says on page 2 of this volume, the "problems of the stem cell<br />

are a paradigm for the basic problems of cell diversification". This symposium,<br />

which was held in Manchester in April 1977, was unusual in that many<br />

developing systems were considered from the viewpoint of stem cells (or<br />

rather "cell lineage") which are not usually so considered, e.g. developing<br />

and regenerating limbs (Wolpert), the mammalian embryo (Papaioannou et at.),<br />

218<br />

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