ATLAS OF STRABISMUS

Soon you can have
exactly that at your fingertips...
with the publication of
ATLAS OF STRABISMUS
By Gunter K. von Noorden, M,D., and A. Edward Maumenee, M.D.
Here is the strabismus book that you and your colleagues have long
awaited . . . one that demonstrates, step-by-step, those diagnostic tests
that (I) have, in the authors' extensive experience, proved most practical,
and (2) do not require elaborate equipment and extensive space.
ATLAS OF STRABISMUS offers you an extremely practical combination
. . . informative text that tells you what to do and why. plus illustrations
that show you precisely how to do it. The original drawings by
Robert B. Wingate, M.S., F.R.S.A., and clinical photographs offer you a
total of 115 excellent illustrations of which 29 are printed in two colors.
ATLAS OF STRABISMUS begins with a broad discussion of the anatomy
and physiology of the extra-ocular muscles, emphasizing clinically
significant features. It then describes and illustrates for you;
• types of pseudostrabismus and how to recognize them;
• qualitative and quantitative diagnosis of strabismus;
• how to evaluate the sensory and motor status of the patient;
• diagnosis and etiology of accommodative esotropia,
convergence spasm, strabismus fixus, and ocular myopathy.
Never before has strabismus been the subject of an atlas. For the first
time, a single source provides you with graphic descriptions of: the
most recent methods for diagnosis of sensory adaptations in strabismus;
diagnosis and management of the A- and V-patterns; the most recent
tests for retinal correspondence; and the different forms of anihlyopia.
So you can begin using this new atlas just as soon as it is published, we
invite you to reserve your copy now, for free 30-day examination.
By GUNTER K. von NOORDEN, M.D., Associate Professor of Ophthalmology,
and A. EDWARD MAUMENEE, M.D., Professor of Ophthalmology, The Wilmer
Institute of Ophthalmology, The Johns Hopkins University, School of Medicine
and Hospital, Baltimore. Maryland. Illustrated by ROBERT B. WINGATE, M.S.,
F.R.S.A. Publication date: October. 1967. 188 pages plus FM I-XIV, 8%"x 11",
with 115 illustrations including 29 in two colors. Price, $17.50.
Please send me a copy of von Noorden,
ATLAS OF STRABISMUS, priced at $17.50.
I understand that I can save delivery charges
by including my remittance with this order.
IO-1267
THE C. V. MOSBY COMPANY
3207 Washington Boulevard
6D
Fig. 106. A, Excessive accommodation
in an uncorrected hy
permetropia of 3 D, and exces
sive accommodative convergence
uncompensated for by relative
fusional divergence, have led to
an esodeviation at near fixation.
B, Photograph of a patient with
accommodative esotropia. C,
Correction of the hyperopic re
fractive error leads to straighten
ing of the eyes. D, The effect
of +3 D spherical glasses in a pa
tient with corrected hypermetro
pia.
ublishers
. Louis, Mo. 63103
Payment enclosed {Same return privilege)
Address.
City .State .Z.p.
30-day approval offer good only in continental U.S. and Canada
M.D.

echothiophate iodide
a convenient 24 hour solution to the 24 hour problem of tension control

long-acting...provides smooth control of
intraocular pressure in the critical "nighttime" hours
for the patient with chronic
simple (open-angle) or aphakic glaucoma
k
flattens intraocular pressure
curves to provide smoother,
more consistent tension control
"In this series [clinical trial involving
52 eyes of 41 glaucoma
patients], echothiophate [PHOS-
PHOLINE IODIDE], with one exception,
appeared to eliminate large
fluctuations in intraocular pressure,
an effect probably related to its long duration
of action."* It provides consistently lower pressures
than pilocarpine.*
minimizes the risk of forgotten doses
Since patients are much more likely to adhere
strictly to directions with a medication that need
be taken only once or twice rather than three to
five times a day, the less frequent administration
of PHOSPHOLINE IODIDE (echothiophate iodide)
gives greater likelihood that the eyedrops will actually
be taken. 3 Moreover, with bedtime—and occasionally
morning —dosage sufficing to control
most cases, the patient need not always carry the
drug with him during his working hours/
helps prevent deterioration of vision
"Because of the long duration of its action, it would
seem that phospholine iodide could be used to
maintain control throughout the night and, by providing
uninterrupted therapy, prevent or delay the
progression of the disease." 5
three concentrations
provide flexibility of dosage
PHOSPHOLINE IODIDE {echothiophate iodide) is available
in three concentrations—0.06%, 0.125%, and
0.25%—that "permit individualized treatment without
increasing the frequency of application, depending
on the status and response of the case."*
concomitant therapy
Concomitant administration with PHOSPHOLINE
IODIDE (echothiophate iodide) of sympathomi-
metics or carbonic anhydrase inhibitors Is permissible
as indicated.
Indications: Chronic simple (open-angle) glaucoma,
secondary glaucomas, especially aphakic,
chronic angle closure glaucoma after peripheral
iridectomy.
Warning: Medication should be temporarily discontinued
if (otherwise unexplainable) persistent
diarrhea, profuse sweating, or muscle weakness
should occur.
Antidote: Atropine, 2 mg, parenterally; artificial
respiration, if needed.
Precautions and Side Effects: Browache, dimness
of vision, or ciliary and conjunctiva! injection may
occur during initial therapy but will usually disappear
after 5 to 10 days of continuous treatment.
Iris cysts may occur in children and occasionally
in adults. They usually do not interfere with continuation
of treatment and will regress on reduction
of dosage. Retinal detachment has occurred,
and PHOSPHOLINE IODIDE (echothiophate iodide)
should be used with extreme caution, if at all,
where there is a history of this disorder. It may
cause or activate acute iritis, and slit lamp examination
before initial therapy and several times
during the first week of therapy has been recommended.
If patient is receiving other anticholinesterases
systemically, the possibility of drug interaction
must be considered. Prior to surgery,
PHOSPHOLINE IODIDE (echothiophate iodide) is not
generally recommended in angle closure glaucoma,
but it may, nevertheless, be used, under close
supervision, in the noncongestive phase if the
tension is elevated and operation is refused or
contraindicated.
Supplied: 3.0 mg. package for 0.06% solution;
6.25 mg. package for 0.125% solution; 12.5 mg.
package for 0.25% solution. Each solution also contains
mannitol, chlorobutanol (chloral derivative),
boric acid, and sodium phosphate.
References: 1. Lawlor, R. C, and Lee, Pei-Fei: Am. J. Ophth.
49:808 (Apr.) 1960. 2. Gray, L. F., and Robinson, J. P.:
Ibid 49:1162 (May) 1960. 3. Coyle, J. T., Weiner, A.,
Frank, P., and Leonard, A.: Ibid 52:867 (Dec.) 1961.
4. Hirsch-Hoffman, A. M.: Ophthalmologies 247:96 (Dec.)
1964. 5. Klayman, J., and Taffet, S.: Am. J. Ophth. 55:1233
(June) 1963.
The Ophthalmos Division
AYERST LABORATORIES
New York, N.Y. 10017 • Montreal, Canada

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offer you the benefit of their experience in such highly significant
areas as: prosthetic implants in and around the orbit;
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palpebral paralysis; and transcranial decompression for relief
of exophthalmos. These distinguished presentations are amplified
with more than 340 pertinent illustrations, and clinically
oriented round table discussions. For a better idea of what it
offers you, check the list of topics below. Then reserve your
copy for free 30-day examination.
Provides you with authoritative, practical
solutions to problems in these areas:
Prosthetic implants in and
around the orbit
Epinephrine and general
anesthesia
Banked eye tissue
Tumors of eyelid
Tumors of orbit
Repair of acute traumatic
defects of the lacrimal
system
Thermal burns of the face
and eyelid
Complications of fractures of
the orbital floor
Congenital anomalies
Facial paralysis
Enophthalmos
Exophthalmos
Correction of severely
contracted socket
By Co-Chairmen: BYRON SMITH, M.D. and JOHN MARQUIS CONVERSE, M.D.
Secretaries: DONALD WOOD-SMITH, M.D., F.R.C.S.E. and MARGARET OBEAR,
M.D. and 53 contributors. Publication date: November, 1967. Approx. 575
pages, 6 3 /4" x 9 3 /4", with 344 illustrations. Price, $31.00.
Fig. 25-5. Free tarsal graft to the lid. A. Excision of the donor graft. B. Closure of
the defect. C to E, Insertion of the donor graft into the lid margin with a continuous
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for oral management
of many types
of glaucoma
DARANIDE
DICHLORPHENAMIDE
usually
most successful
when given
in conjunction
with miotics
* An oral carbonic anhydrase inhibitor
which frequently reduces increased
intraocular pressure.
• Often provides effectiveness over a
prolonged period of administration.
•Onset of action usually within an
hour of administration.
• Effective for approximately 6 to 12
hours.
• Effective as a means of enhancing
the pressure-regulating effects of
topical miotic agents, thus facilitating
smoother management for
the glaucoma patient.
Contraindications:To avoid blood pH
decreases below 7.20, do not use if
arterial pCO2 greater than 63 mm.
Hg; hepatic insufficiency; renal failure;
hyperchloremic acidosis; adrenocortical
insufficiency.
Indications: Treatment of chronic simple
(wide angle) glaucoma, acute congestive
(narrow angle) glaucoma, chronic congestive
glaucoma, secondary glaucoma (acute
phase), and preoperative control of intraocular
tension of glaucoma; respiratory
acidosis of pulmonary insufficiency. Use
in conjunction with other agents as indicated.
Precautions and Side Effects: Side effects
(characteristic of carbonic anhydrase
inhibitors) may include gastrointestinal
disturbances (anorexia, nausea,
vomiting), constipation, urinary frequency,
mild skin eruptions, pruritus, headache,
weakness, nervousness, globus
hystericus, sedation, lassitude, depression,
confusion, disorientation, dizziness,
ataxia, tremor, tinnitus, paresthesias of
hands, feet, tongue. If they occur, reduce
dosage or discontinue drug temporarily.
As with other carbonic anhydrase inhibitors:
agranulocytosis, thrombocytopenia,
or renal calculi are possible; a
close check on electrolyte balance, blood
pH, and blood gases should be kept during
therapy. In high doses, may cause
some decrease in renal blood flow and
glomerular filtration rate.
Use with caution in severe respiratory
acidosis or in the presence of chronic
pulmonary infection; discontinue if blood
pH falls below 7.20.
Supplied: Tablets DARANIDE, containing
50 mg. dichlorphenamide each, in bottles
of 100.
Before prescribing or administering, read
product circular with package or available
on request.
MERCK SHARP A DOHME
Division of Merck & Co, INC. West Point. Pa 19486
whore today's theory la tomorrow's therapy

STATEMENT OF OWNERSHIP, MANAGEMENT AND CIRCULATION (Act of October 23, 1962; Section
4369, Title 39, United States Code). 1. Date of filing: October 2, 1967. 2. Title of publication: INVESTIGATIVE
OPHTHALMOLOGY. 3. Frequency of issue: Bi-monthly. 4. Location of known office of publication: 3207
Washington Blvd., St. Louis, Missouri 63103. 5. Location of the headquarters or general business offices of the
publishers: Same as 4. 6. Names and addresses of publisher, editor, and managing editor: Publisher—The C. V.
Mosby Company, 3207 Washington Blvd., St. Louis, Missouri 63103; Editor—Dr. Bernard Becker, Washington
University, St. Louis, Mo.; Managing editor—None. 7. Owner: Association for Research In Ophthalmology,
660 S. Kingshighway, St. Louis, Missouri 63110. 8. Known bondholders, mortgagees, and other security holders
owning or holding 1 percent or more of total amount of bonds, mortgages or other securities: None. 9. For
completion by nonprofit organizations authorized to mail at special rates (Section 132.122, Postal Manual)
INVESTIGATIVE OPHTHALMOLOGY is mailed at the regular second-class rates.
10.
A. Total no. copies printed (Net press run)
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1. Sales through dealers and carriers, street vendors and counter sales
2. Mail subscriptions
C. Total paid circulation
D. Free distribution (including samples) by mail, carrier or other means
E. Total distribution (Sum of C and D)
F. Office use, left-over, unaccounted, spoiled after printing
G. Total (Sum of E & F—should equal net press run shown in A)
I certify that the statements made by me above are correct and complete.
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preceding 12 months
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WHEN YOU MOVE, PLEASE—
(1) Notify us to change your address—allow us six weeks to make the change.
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Electronic
Schiotz
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Model 701 is made with space-age
engineering quality and skills to afford you
professional assurance in tension
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IBTCL BERKELEY TONOMETER CO.
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December 19fi7
GOLDBERG and SARIN
ULTRASONICS IN
OPHTHALMOLOGY
By 14 World Authorities
fly Richard Earl Goldberg, M.O., and Lov K. Serin,
M.D, Both of Wills Eye Hospital, Philadelphia.
This pioneering book unlocks a wealth of
practical new information on the current
applications and expanding capabilities of
ultrasonography in diagnosing and treating
diseases of the eye.
Use of time-amplitude (A-mode) techniques
in measurement of the globe and diagnosis
of pathological conditions is fully explained.
The more complex methods of intensity-modulated
(B-scan) ultrasonography are described
in detail. The use of ultrasound to measure
the refractive elements of the eye and in the
location and removal of foreign bodies is
also thoroughly outlined.
223 pp. 190 figs. $24.00 October, 1967
W. B. Sounders Company
W. Washington Sq., Phila., Pa. 19105
10-12-67
Please send and bill me;
• Goldberg and Sarin—ULTRASONICS IN
OPHTHALMOLOGY, $24.00
Name
Address
Zip
Page 29

Page 30
Allergan Pharmaceuticals
Herplex Fourth Cover
Ayerst Laboratories
Epitrate 20, 21
Phospholine Iodide 24, 25
Barnes-Hind Ophthalmic Products
Eppy 14
The Comfort Cycle 10, 11
Berkeley Tonometer Company
Electronic Schiotz Tonometer 29
Broemmel Pharmaceuticals
Pilo B Second Cover
Davis & Geek
Sutures 4
Frigitronics, Inc.
Micro Cryosurgery 2
Lederle Laboratories
Diamox Sequels 16. 17
Index to advertisers
Madland Laboratories, Inc.
Glaucon 6
Merck Sharp & Dohme
Daranide 27
NeoDecadron 8, 9
Minnesota Mining & Manufacturing
Company
Steri-Drape/Blenderm 18, 19
Olympus Corporation of America
MTX operating microscope 22
Person & Covey, Inc.
PE Ophthalmics 12
Sanders Company, W. B.
Book 29
White Laboratories, Inc.
Metimyd 15
Sodium Sulamyd 13
While every precaution is taken to insure accuracy, we cannot guarantee against the possibility of an
occasional change or omission in the preparation of this index.
Investigative Ophthalmology

John M. McLean, M.D., F.A.C.S., guides you, step-by-step,
through the complexities of glaucoma surgery
A New Atlas!
ATLAS OF GLAUCOMA SURGERY
To own and use a copy of this new atlas is the next best
thing to actually performing glaucoma surgery under the
skilled supervision of John M. McLean, M.D., F.A.C.S.,
one of the foremost ophthalmic surgeons experienced in
the surgical management of this serious disorder. The
step-by-step instruction of Dr. McLean can facilitate your
initial diagnosis of the disease and aid you in performing
tests to determine the exact type of glaucoma present.
Further, Dr. McLean's superb guidance can aid your
evaluation of glaucoma cases; speed your selection of the
best corrective method; and enhance your surgical skills.
You will especially appreciate the author's understandable
presentation of such recent advances as cautery
sclerostomies and cryosurgery of the ciliary body. Equally
important is Dr. McLean's careful consideration of
possible complications, including management of the late,
serious complication of nuclear cataracts.
The superbly executed, step-by-step drawings, by
outstanding medical illustrator, Miss Shirley Baty,
make Dr. McLean's explicit instructions even more
understandable and valuable to you. The few
illustrations shown here only preview the quality,
pertinence and aptness you can expect from every
illustration in this new atlas.
Your professional library is not complete without
a copy of ATLAS OF GLAUCOMA SURGERY.
Order your copy today.
By JOHN M. McLEAN, M.D., F.A.C.S. Professor of Clinical
Surgery (Ophthalmology), Cornell University Medical College,
New York, N. Y.; Attending Surgeon-in-Charge (Ophthalmology),
New York Hospital, New York, N. Y. Illustrated by
SHIRLEY BATY. Publication date: December, 1967. Approx.
128 pages, 8Vi" X 11", 88 plates of illustrations. Price, $17.50.
The C. V. MOSEY Company
3207 Washington Boulevard
Publishers
SI Louis. Mo. 63103
D
Ftg. 83. Goniotomy. Goniotomy is best performed
under direct vision with some magnification. Surgical
contact lenses are available with a handle (A) or
for support with the finger (B) or forceps (D). As
on alternate, the onterior chamber ma/ be emptied
of aqueous and refilled by air. This will so alter the
optics as to make the angle gonioscopicolly visible
but without the magnification provided by the contact
lenses. It can be done as a separate maneuver
or with a special goniotomy knife which is made on
the end of a fine needle (C). This same instrument
is then used throughout the operation.

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