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Chinese Academy of Sciences (PDF) - low res version

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24<br />

CAS/In Focus<br />

Figure 2. Illustration <strong>of</strong> the Quantum Science Satellite.<br />

• Dark Matter Particle Explorer (DAMPE): The explorer will investigate<br />

dark matter particles from deep space by high-<strong>res</strong>olution observation<br />

<strong>of</strong> gamma-rays as well as electron spectra and their distribution in<br />

space. It will also help scientists study the motion and acceleration <strong>of</strong><br />

cosmic rays in the galaxy by measuring the energy spectra <strong>of</strong> heavy ions.<br />

• ShiJian-10 (SJ-10): Using recoverable satellite technology, SJ-10 focuses<br />

on the behavior <strong>of</strong> matter and life activities in space. It will carry<br />

out experiments in microgravity on heat and mass transport in fluid, biospace<br />

adaptation, and mutation and gene exp<strong>res</strong>sion.<br />

• KUAFU Mission (KUAFU): Named after the legendary <strong>Chinese</strong> figure<br />

who chases the Sun, the project will help scientists study solar influences<br />

on earth space weather. It consists <strong>of</strong> three satellites, one located at<br />

L1 (the point at which an object experiences the same gravitational pull<br />

from both the Earth and the Sun, al<strong>low</strong>ing it remaining in the same position<br />

relative to these bodies) and two in polar orbits. It is a cooperative<br />

mission with international collaborations. China will launch one satellite,<br />

KUAFU A, to the L1 point.<br />

• Intensive Study <strong>of</strong> Future Space Science Missions: Fol<strong>low</strong>ing the<br />

space science strategic plan, this project aims to intensively study new<br />

science missions, taking into account scientific objectives, optimization<br />

<strong>of</strong> plan implementation, and development <strong>of</strong> key technologies, in preparation<br />

for implementing the missions during the 13th Five-Year Plan period<br />

(2016–2020).<br />

Research<br />

Stem Cells and Regenerative Both neurodegener-<br />

Medicine<br />

Research on stem cells and regenerative ative disorders and<br />

medicine has flourished in China in the<br />

last decade, despite some hurdles that liver diseases have<br />

have limited their application. An intensive<br />

<strong>res</strong>earch program to study stem cells was a major impact on<br />

launched in order to understand the regulatory<br />

mechanisms in these cells, inves- human health.<br />

tigate the potential for stem cell therapy,<br />

and establish standards and ethics for future applications.<br />

Both neurodegenerative disorders and liver diseases have a major impact<br />

on human health. Compared with traditional medical treatments, regenerative<br />

medicine <strong>of</strong>fers a promising approach for therapy. Research into the<br />

developmental origins <strong>of</strong> nerves and liver tissue will provide a theoretical<br />

basis for the clinical application <strong>of</strong> stem cells and regenerative medicine.<br />

This program has established a system-wide academic network to support<br />

the <strong>res</strong>earch involving more than 80 <strong>res</strong>earch groups from four centers <strong>of</strong><br />

stem cell and regenerative medicine <strong>res</strong>earch located in Beijing, Shanghai,<br />

Guangzhou, and Kunming, as well as 17 other institutes studying life science,<br />

material science, chemistry, and biomechanics.<br />

The basic strategy is to study liver, mesenchyme, and neural stem cells<br />

originating from the three germ layers: the endoderm, mesoderm, and ectoderm—from<br />

which stem cell differentiation, development, and organ formation<br />

take place—so as to integrate basic theoretical <strong>res</strong>earch with new<br />

strategic applications <strong>of</strong> stem cells and regenerative medicine. Results from<br />

the program will clarify the origin, maintenance, differentiation, and function<br />

<strong>of</strong> stem cells during normal and pathological development <strong>of</strong> important<br />

organs. The program also focuses on identifying important targets for stem<br />

cell regulation, exploring drug candidates based on stem cell factors and<br />

functional regulators, and establishing a translational <strong>res</strong>earch system for<br />

stem cell technologies. The ultimate goals are to discover the basic mechanisms<br />

underlying stem cell biology; to identify the roles <strong>of</strong> stem cells in the<br />

origin, formulation, and regeneration <strong>of</strong> tissues and organs; to develop new<br />

strategies for precisely regulating stem cells; to implement clinical applications<br />

<strong>of</strong> stem cells in the repair <strong>of</strong> pathological damage; and to promote the<br />

development <strong>of</strong> regenerative medicine.<br />

Contact: Pr<strong>of</strong>essor Zhou Qi, zhouqi@ioz.ac.cn<br />

• Advanced Research <strong>of</strong> Space Science Missions and Payloads:<br />

This <strong>res</strong>earch is intended to advance key technologies for future space<br />

science satellites by supporting a related group <strong>of</strong> <strong>res</strong>earch subjects,<br />

including innovative concepts for future space science missions, key<br />

technologies <strong>of</strong> payloads, ground calibrations, and short-term flight<br />

CAS; OF<br />

demonstrations.<br />

With the intention <strong>of</strong> encouraging cooperation in order to stay at the<br />

COURTESY<br />

forefront <strong>of</strong> discovery, this program is open to the entire science community<br />

TOP)<br />

for cooperation, with opportunities for mission to mission cooperation, payload<br />

piggybacking with foreign partners, ground support, and data sharing.<br />

(FROM<br />

“Tiny,” the mouse developed from induced pluripotent stem cells<br />

through tetraploid complementation.<br />

Contact: Pr<strong>of</strong>essor Wu Ji, wuji@nssc.ac.cn. CREDIT:<br />

COURTESY OF THE INSTITUTE OF ZOOLOGY, CAS

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