Sirtex Cover.proof 11 - School of Educators
Sirtex Cover.proof 11 - School of Educators
Sirtex Cover.proof 11 - School of Educators
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74<br />
Glossary <strong>of</strong> Terms and References<br />
Technical Terms<br />
Carcinoma A medical term for cancer<br />
Chemotherapy The administration <strong>of</strong> anti cancer drugs to patients with cancer<br />
Cryotherapy Treatment <strong>of</strong> cancer by freezing in order to destroy it<br />
Doxorubicin An anti-cancer drug that is widely used in the treatment<br />
<strong>of</strong> cancer patients<br />
FDA Food and Drug Administration <strong>of</strong> the USA Department<br />
<strong>of</strong> Health and Human Services<br />
FUDR Floxuridine, a type <strong>of</strong> anti-cancer drug<br />
Hepatic Artery The main artery supplying blood to the liver<br />
Hyperthermia The treatment <strong>of</strong> cancer by raising the temperature <strong>of</strong> the cancer in<br />
order to destroy it<br />
Lipiodol An oily liquid that is used to mix with anti-cancer drugs and which<br />
can be injected into the hepatic artery <strong>of</strong> patients with liver cancer in<br />
order to concentrate the drug in the cancerous tissues<br />
Metastases Secondary cancers that occur as a result <strong>of</strong> a cancer at another site<br />
spreading to new tissues <strong>of</strong> the body<br />
Phase I Trial A clinical experiment in which new therapies are tested predominantly<br />
to determine their safety at different doses<br />
Phase II Trial A clinical experiment in patients that assesses whether<br />
a new treatment has a beneficial effect on the patient<br />
Phase III Trial A clinical experiment in patients in which a new experimental<br />
treatment is compared with what is regarded as ‘standard practice’<br />
SIRT Selective Internal Radiation Therapy is the medical procedure in which<br />
SIR-Spheres ® is administered to patients in order to treat their cancer<br />
TGA Therapeutic Goods Administration <strong>of</strong> Australia<br />
TACE Trans Arterial Chemo-Embolisation is the technique used to treat liver<br />
cancer whereby an anti-cancer drug is mixed with lipiodol and<br />
injected into the main artery supplying blood to the live<br />
References<br />
Gray BN, Stribley K, Heggie J, Chmiel R,<br />
Bennett RC; Distribution <strong>of</strong> radioactive<br />
microspheres in liver parenchyma and tumour<br />
tissue. Aust. N.Z. J. Surg. 1983, 53;366.<br />
Stribley KV, Gray BN, Chmiel R, Heggie<br />
JCP, Bennett RC; Internal radiotherapy for<br />
hepatic metastases; The homogeneity <strong>of</strong> hepatic<br />
arterial blood flow. Surg. Res. 1982, 33;17-24<br />
Stribley KV, Gray BN, Chmiel R, Heggie<br />
JCP, Bennett RC; Internal radiotherapy for<br />
hepatic metastases; The blood supply <strong>of</strong> hepatic<br />
metastases. Surg.Res. 1982, 33;25-32<br />
Chamberlain M, Gray BN, Heggie JCP,<br />
Chmiel R, Bennett RC; Hepatic metastases;<br />
A physiological approach to treatment. Brit. J.<br />
Surg. 1983, 70;596-598.<br />
Burton MA, Gray BN, Self GW, Heggie JC,<br />
Townsend PS; Manipulation <strong>of</strong> experimental<br />
rat and rabbit liver tumour blood flow with<br />
Angiotensin-2. Cancer Res. 1985, 45;5390-<br />
5393.<br />
Meade V, Burton MA, Gray BN, Self G;<br />
Distribution <strong>of</strong> different sized microspheres in<br />
experimental hepatic tumours. Europ. J.<br />
Cancer & Clin. Oncol. 1987, 23;37-41.<br />
Burton MA, Gray BN; Redistribution <strong>of</strong><br />
blood flow in experimental hepatic tumours<br />
with Nor-Adrenaline and Propanalol. Brit. J.<br />
Cancer. 1987, 56;585-588.<br />
Burton MA, Gray BN, Colletti A; Effect <strong>of</strong><br />
Angiotensin-2 on blood flow in the transplanted<br />
sheep squamous cell carcinoma. Europ. J.<br />
Cancer Clin. Oncol. 1988, 24(8);1373-1376.<br />
Burton MA, Gray BN; Intra-operative<br />
dosimetry <strong>of</strong> Yttrium-90 in liver tissue.<br />
Nuclear Med. Biol. 1989, 16; 495-498.<br />
Archer S, Gray BN; The vascularisation <strong>of</strong><br />
small liver metastases. Brit. J. Surgery 1989,<br />
76;545-548.<br />
Burton MA, Gray BN, Klemp P, Kelleher D,<br />
Hardy N; Selective Internal Radiation Therapy;<br />
Distribution <strong>of</strong> radiation in the liver. Europ.<br />
J. Cancer Clin. Oncol. 1989, 25;1487-<br />
1491.<br />
Gray BN, Burton MA, Kelleher D,<br />
Anderson J, Klemp P; Selective Internal<br />
Radiation (SIR) Therapy for treatment <strong>of</strong> liver<br />
metastases; Measurement <strong>of</strong> response rate.<br />
Surg. Oncol. 1989, 42:192-196.<br />
Klemp PFB, Perry AM, Fox RA, Gray BN,<br />
Burton MA; Aspects <strong>of</strong> radiation protection<br />
during the treatment <strong>of</strong> liver cancer using<br />
yttrium-90 labelled microspheres. Rad.<br />
Protect. Aust. 1989; 7; 70-73.<br />
Archer SG, Gray BN; Comparison <strong>of</strong> portal<br />
vein chemotherapy with hepatic artery<br />
chemotherapy in the treatment <strong>of</strong> liver<br />
micrometastases. Amer. J. Surgery 1990,<br />
159:325-329.<br />
Gray BN, Matz L, Burton MA, Kelleher D,<br />
Klemp P; Tolerance <strong>of</strong> the liver to Yttrium-90<br />
irradiation. Int. J. Rad. Oncol. Biol. Phys.<br />
1990, 18;619-623.<br />
Kelleher DK, Burton MA, Codde JP, Gray<br />
BN; A model for localised hyperthermia <strong>of</strong><br />
liver tumours in the rabbit. Regional Cancer<br />
Treat. 1990, 3:26-30.<br />
Burton MA, Jones C, Trotter J, Gray BN,<br />
Codde JP; Efficacy <strong>of</strong> ion exchange resins for<br />
anti-tumour drug delivery. Regional Cancer<br />
Treat. 1990, 3;36-39.