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Human Toxicity, Environmental Impact and Legal Implications of

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TABLE OF CONTENTS<br />

Acknowledgements 1<br />

Potential conflicts <strong>of</strong> interest 1<br />

Limitations 1<br />

Disclaimer 1<br />

1.0 INTRODUCTION 5<br />

2.0 THE MAIN FINDINGS ON HUMAN HEALTH TOXICITY AND THE<br />

ENVIRONMENTAL IMPACT OF WATER FLUORIDATION 7<br />

2.1 HEALTH RISKS 11<br />

2.2 ENVIRONMENTAL RISKS 14<br />

2.3 INADEQUATE RISK ASSESSMENT 16<br />

3.0 FLUOROSILICICTES AND DRINKING WATER 18<br />

4.0 ENVIRONMENTAL FATE OF FLUORIDE 24<br />

4.1 Fluoride in Surface Water <strong>and</strong> Sewer Systems 26<br />

4.2 Fluoride <strong>and</strong> Fisheries 28<br />

4.3 Fluoride as a Pollutant in Soil. 31<br />

4.4 Fluoride in our Food 33<br />

4.5 Ingested Fluoride 38<br />

5.0 HUMAN CHEMISTRY: FLUORIDE INTERACTION WITH CALCIUM AND<br />

MAGNESIUM 44<br />

5.1 Hypocalcaemia 46<br />

5.2 Sarcoidosis 49<br />

5.3 Relationship to Calcium Bio-availability in Drinking Water 50<br />

5.4 Fluoride Intake <strong>and</strong> Health Monitoring Programs 50<br />

5.5 Calcium Disorders <strong>and</strong> Gastroenteritis 51<br />

5.6 Additional Health Risks from Low Calcium <strong>and</strong> Magnesium 52<br />

5.7 Vulnerable Populations: Disease Clusters in Irel<strong>and</strong> 57<br />

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