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HUMAN TOXICITY, ENVIRONMENTAL IMPACT AND LEGAL IMPLICATIONS OF WATER FLUORIDATION<br />

Aluminium-based products, particularly those for water treatment (e.g.,<br />

aluminium sulfate [alum], polyaluminium chloride [PAC], <strong>and</strong> sodium<br />

aluminate), are commonly used as compounds in water treatment in Irel<strong>and</strong>.<br />

It is also known that the relative risk <strong>of</strong> having Alzheimer‘s disease is increased<br />

when individuals have a high amount <strong>of</strong> alumimum in the brain coupled with<br />

low levels <strong>of</strong> fluoride. 297 Concern over the use <strong>of</strong> aluminium compounds as<br />

coagulants in drinking water treatment plants using fluoridation (as well as in<br />

effluent wastewater treatment plants) exists, since their addition usually results<br />

in an increase in the amount <strong>of</strong> aluminium in finished water.<br />

Further important details on the toxicological pr<strong>of</strong>ile <strong>of</strong> aluminium fluorides<br />

have been documented in a number <strong>of</strong> important studies that demonstrated<br />

serious kidney abnormalities <strong>and</strong> blood vessel deteriorations. 298 , 299 , 300 One<br />

group <strong>of</strong> investigators has proposed that the aluminium present in infant<br />

formulas played a role in the development <strong>of</strong> aluminium toxicity in two<br />

neonates with renal fai1ure. 301 The Varner et al. research team concluded<br />

that the alterations <strong>of</strong> the blood vessels from exposure to aluminium fluoride<br />

may be a primary event, triggering neuro-degenerative diseases. It has been<br />

reported that in respect to the study <strong>and</strong> cause <strong>of</strong> Alzheimer´s disease, the<br />

long-term action <strong>of</strong> aluminium fluoride also represents “a serious <strong>and</strong> potent<br />

risk factor for the development <strong>of</strong> this new epidemic threat to human<br />

civilization”. 302,303.,304<br />

Pr<strong>of</strong>essor Strunecká (Department <strong>of</strong> Physiology <strong>and</strong> Developmental Biology,<br />

Charles University, Prague), found that “aluminium fluoride might induce the<br />

alterations <strong>of</strong> homeostasis, metabolism, growth <strong>and</strong> differentiation <strong>of</strong> the<br />

living organism. The long-term synergistic effects <strong>of</strong> these ions in living<br />

environments <strong>and</strong> their hidden danger for human health are not yet fully<br />

recognized‖. 305<br />

Fluorides <strong>and</strong> fluoride-aluminium compounds have been demonstrated to<br />

297 Belovjovic, G., Jakovlevic, B. (1999) Aluminum <strong>and</strong> Alzheimer‘s disease. Spr.<br />

ArArh. Celok 126: 283-289.<br />

298 Varner JA, Jensen KF, Horvath W, Isaacson RL, Chronic administration <strong>of</strong> aluminumfluoride<br />

or sodium-fluoride to rats in drinking water: alterations in neuronal <strong>and</strong><br />

cerebrovascular integrity, Brain Res. 1998 Feb 16;784(1-2):284-98<br />

299 Isaacson RL, Varner JA, Jensen KF, Toxin-induced blood vessel inclusions caused<br />

by the chronic administration <strong>of</strong> aluminum <strong>and</strong> sodium fluoride <strong>and</strong> their implications<br />

for dementia, Ann N Y Acad Sci. 1997 Oct 15;825:152-66..<br />

300 Varner JA, Horvath WJ, Huie CW, Naslund HR, Isaacson RL, Chronic aluminum<br />

fluoride administration, I. Behavioral observations, Behav Neural Biol. 1994<br />

May;61(3):233-41<br />

301 Freundlich M, zilleruelo C, Ahitbol C, Strauss J, Faugere MC, Malluche<br />

NH. Infant formula as a cause <strong>of</strong> aluminum toxicity in neonatal uraemia.<br />

Lancet. 1985;2:527-529<br />

302 STRUNECKÁ A: Aluminium plus fluoride: a new deadly duo in Alzheimer´s disease.<br />

The News (A Hoechst Marion Roussel Report <strong>of</strong> International Medical Opinion) 1: 10-<br />

11, 1999.<br />

303 STRUNECKÁ A, PATOČKA J: Pharmacological <strong>and</strong> toxicological effects <strong>of</strong><br />

alumin<strong>of</strong>luoride complexes. Fluoride 32: 230 -242, 1999a.<br />

304 STRUNECKÁ A, PATOČKA J: Re-evaluation <strong>of</strong> the participation <strong>of</strong> aluminium in<br />

Alzheimer´s disease (in Czech). Čs fyziol 48: 9-15, 1999b<br />

305 STRUNECKÁ A et al: Fluoride Plus Aluminum: Messengers <strong>of</strong> False Information,<br />

Physiological Research 51: 557-564, 2002.<br />

www.enviro.ie Page 65

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