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20 - World Journal of Gastroenterology

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perpermeability and endotoxemia prior to development <strong>of</strong><br />

alcoholic steatohepatitis in rats. J Hepatol <strong>20</strong>09; 50: 538-547<br />

31 Petrasek J, Dolganiuc A, Nath B, Hritz I, Kodys K, Catalano,<br />

Kurt-Jones E, Mandrekar P, Szabo G. Hepatocytespecific<br />

IRF3 and type I interferons are protective in alcoholinduced<br />

liver injury I mice via cross-talk with macrophages.<br />

Hepatology <strong>20</strong>11; In press<br />

32 Mutlu E, Keshavarzian A, Engen P, Forsyth CB, Sikaroodi<br />

M, Gillevet P. Intestinal dysbiosis: a possible mechanism <strong>of</strong><br />

alcohol-induced endotoxemia and alcoholic steatohepatitis<br />

in rats. Alcohol Clin Exp Res <strong>20</strong>09; 33: 1836-1846<br />

33 Tang Y, Forsyth CB, Farhadi A, Rangan J, Jakate S, Shaikh M,<br />

Banan A, Fields JZ, Keshavarzian A. Nitric oxide-mediated<br />

intestinal injury is required for alcohol-induced gut leakiness<br />

and liver damage. Alcohol Clin Exp Res <strong>20</strong>09; 33: 12<strong>20</strong>-1230<br />

34 Tang Y, Banan A, Forsyth CB, Fields JZ, Lau CK, Zhang LJ,<br />

Keshavarzian A. Effect <strong>of</strong> alcohol on miR-212 expression in<br />

intestinal epithelial cells and its potential role in alcoholic<br />

liver disease. Alcohol Clin Exp Res <strong>20</strong>08; 32: 355-364<br />

35 Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G,<br />

Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar<br />

BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN,<br />

Hecht FM, Picker LJ, Lederman MM, Deeks SG, Douek DC.<br />

Microbial translocation is a cause <strong>of</strong> systemic immune activation<br />

in chronic HIV infection. Nat Med <strong>20</strong>06; 12: 1365-1371<br />

36 Cassol E, Malfeld S, Mahasha P, van der Merwe S, Cassol<br />

S, Seebregts C, Alfano M, Poli G, Rossouw T. Persistent<br />

microbial translocation and immune activation in HIV-1infected<br />

South Africans receiving combination antiretroviral<br />

therapy. J Infect Dis <strong>20</strong>10; <strong>20</strong>2: 723-733<br />

37 Nowroozalizadeh S, Månsson F, da Silva Z, Repits J, Dabo B,<br />

Pereira C, Biague A, Albert J, Nielsen J, Aaby P, Fenyö EM,<br />

Norrgren H, Holmgren B, Jansson M. Microbial translocation<br />

correlates with the severity <strong>of</strong> both HIV-1 and HIV-2<br />

infections. J Infect Dis <strong>20</strong>10; <strong>20</strong>1: 1150-1154<br />

38 Trøseid M, Nowak P, Nyström J, Lindkvist A, Abdurahman<br />

S, Sönnerborg A. Elevated plasma levels <strong>of</strong> lipopolysaccharide<br />

and high mobility group box-1 protein are associated<br />

with high viral load in HIV-1 infection: reduction by 2-year<br />

antiretroviral therapy. AIDS <strong>20</strong>10; 24: 1733-1737<br />

39 Douek D. HIV disease progression: immune activation, microbes,<br />

and a leaky gut. Top HIV Med <strong>20</strong>07; 15: 114-117<br />

40 Dolganiuc A, Norkina O, Kodys K, Catalano D, Bakis G,<br />

Marshall C, Mandrekar P, Szabo G. Viral and host factors<br />

induce macrophage activation and loss <strong>of</strong> toll-like receptor<br />

tolerance in chronic HCV infection. <strong>Gastroenterology</strong> <strong>20</strong>07; 133:<br />

1627-1636<br />

41 Baum M, Sales S, Jayaweera D, Lai S, Bradwin G, Rafie C,<br />

Page J, Campa A. Coinfection with hepatitis C virus, oxidative<br />

stress and antioxidant status in HIV-positive drug users<br />

in Miami. HIV Med <strong>20</strong>11; 12: 78-86<br />

42 Biasin M, Piacentini L, Lo Caputo S, Naddeo V, Pierotti P,<br />

Borelli M, Trabattoni D, Mazzotta F, Shearer GM, Clerici M.<br />

TLR activation pathways in HIV-1-exposed seronegative<br />

individuals. J Immunol <strong>20</strong>10; 184: 2710-2717<br />

43 Medvedev AE, Lentschat A, Wahl LM, Golenbock DT,<br />

Vogel SN. Dysregulation <strong>of</strong> LPS-induced Toll-like receptor<br />

4-MyD88 complex formation and IL-1 receptor-associated<br />

kinase 1 activation in endotoxin-tolerant cells. J Immunol<br />

<strong>20</strong>02; 169: 5<strong>20</strong>9-5216<br />

44 Adachi Y, Bradford BU, Gao W, Bojes HK, Thurman RG.<br />

Inactivation <strong>of</strong> Kupffer cells prevents early alcohol-induced<br />

liver injury. Hepatology 1994; <strong>20</strong>: 453-460<br />

45 Thakur V, McMullen MR, Pritchard MT, Nagy LE. Regulation<br />

<strong>of</strong> macrophage activation in alcoholic liver disease. J<br />

Gastroenterol Hepatol <strong>20</strong>07; 22 Suppl 1: S53-S56<br />

46 Hritz I, Mandrekar P, Velayudham A, Catalano D, Dolganiuc<br />

A, Kodys K, Kurt-Jones E, Szabo G. The critical role <strong>of</strong><br />

toll-like receptor (TLR) 4 in alcoholic liver disease is independent<br />

<strong>of</strong> the common TLR adapter MyD88. Hepatology<br />

WJG|www.wjgnet.com<br />

Szabo G et al . Alcohol-mediated hepatotoxicity in HIV infection<br />

<strong>20</strong>08; 48: 1224-1231<br />

47 Lau AH, Szabo G, Thomson AW. Antigen-presenting cells<br />

under the influence <strong>of</strong> alcohol. Trends Immunol <strong>20</strong>09; 30: 13-22<br />

48 Fitzgerald-Bocarsly P, Jacobs ES. Plasmacytoid dendritic<br />

cells in HIV infection: striking a delicate balance. J Leukoc<br />

Biol <strong>20</strong>10; 87: 609-6<strong>20</strong><br />

49 Donaghy H, Stebbing J, Patterson S. Antigen presentation<br />

and the role <strong>of</strong> dendritic cells in HIV. Curr Opin Infect Dis<br />

<strong>20</strong>04; 17: 1-6<br />

50 Mandrekar P, Catalano D, Dolganiuc A, Kodys K, Szabo G.<br />

Inhibition <strong>of</strong> myeloid dendritic cell accessory cell function<br />

and induction <strong>of</strong> T cell anergy by alcohol correlates with<br />

decreased IL-12 production. J Immunol <strong>20</strong>04; 173: 3398-3407<br />

51 Szabo G, Mandrekar P. A recent perspective on alcohol,<br />

immunity, and host defense. Alcohol Clin Exp Res <strong>20</strong>09; 33:<br />

2<strong>20</strong>-232<br />

52 Szabo G, Dolganiuc A. Hepatitis C and innate immunity:<br />

recent advances. Clin Liver Dis <strong>20</strong>08; 12: 675-692, x<br />

53 Kim AY, Chung RT. Coinfection with HIV-1 and HCV--a<br />

one-two punch. <strong>Gastroenterology</strong> <strong>20</strong>09; 137: 795-814<br />

54 Dolganiuc A, Kodys K, Kopasz A, Marshall C, Mandrekar P,<br />

Szabo G. Additive inhibition <strong>of</strong> dendritic cell allostimulatory<br />

capacity by alcohol and hepatitis C is not restored by DC<br />

maturation and involves abnormal IL-10 and IL-2 induction.<br />

Alcohol Clin Exp Res <strong>20</strong>03; 27: 1023-1031<br />

55 Núñez M, Lana R, Mendoza JL, Martín-Carbonero L, Soriano<br />

V. Risk factors for severe hepatic injury after introduction<br />

<strong>of</strong> highly active antiretroviral therapy. J Acquir Immune<br />

Defic Syndr <strong>20</strong>01; 27: 426-431<br />

56 Lai KK, Gang DL, Zawacki JK, Cooley TP. Fulminant hepatic<br />

failure associated with 2’,3’-dideoxyinosine (ddI). Ann<br />

Intern Med 1991; 115: 283-284<br />

57 Le Bras P, D’Oiron R, Quertainmont Y, Halfon P, Caquet R.<br />

Metabolic, hepatic and muscular changes during zidovudine<br />

therapy: a drug-induced mitochondrial disease? AIDS<br />

1994; 8: 716-717<br />

58 Fabris P, Tositti G, Manfrin V, Giordani MT, Vaglia A,<br />

Cattelan AM, Carlotto A. Does alcohol intake affect highly<br />

active antiretroviral therapy (HAART) response in HIVpositive<br />

patients? J Acquir Immune Defic Syndr <strong>20</strong>00; 25: 92-93<br />

59 Crabb DW, Galli A, Fischer M, You M. Molecular mechanisms<br />

<strong>of</strong> alcoholic fatty liver: role <strong>of</strong> peroxisome proliferator-activated<br />

receptor alpha. Alcohol <strong>20</strong>04; 34: 35-38<br />

60 Donohue TM. Alcohol-induced steatosis in liver cells. <strong>World</strong><br />

J Gastroenterol <strong>20</strong>07; 13: 4974-4978<br />

61 Ji C, Chan C, Kaplowitz N. Predominant role <strong>of</strong> sterol response<br />

element binding proteins (SREBP) lipogenic pathways<br />

in hepatic steatosis in the murine intragastric ethanol<br />

feeding model. J Hepatol <strong>20</strong>06; 45: 717-724<br />

62 Song Z, Zhou Z, Deaciuc I, Chen T, McClain CJ. Inhibition <strong>of</strong><br />

adiponectin production by homocysteine: a potential mechanism<br />

for alcoholic liver disease. Hepatology <strong>20</strong>08; 47: 867-879<br />

63 Chen X, Sebastian BM, Tang H, McMullen MM, Axhemi A,<br />

Jacobsen DW, Nagy LE. Taurine supplementation prevents<br />

ethanol-induced decrease in serum adiponectin and reduces<br />

hepatic steatosis in rats. Hepatology <strong>20</strong>09; 49: 1554-1562<br />

64 Zeng T, Xie KQ. Ethanol and liver: recent advances in the<br />

mechanisms <strong>of</strong> ethanol-induced hepatosteatosis. Arch Toxicol<br />

<strong>20</strong>09; 83: 1075-1081<br />

65 Sutinen J, Häkkinen AM, Westerbacka J, Seppälä-Lindroos A,<br />

Vehkavaara S, Halavaara J, Järvinen A, Ristola M, Yki-Järvinen<br />

H. Increased fat accumulation in the liver in HIV-infected<br />

patients with antiretroviral therapy-associated lipodystrophy.<br />

AIDS <strong>20</strong>02; 16: 2183-2193<br />

66 Estrada V, Serrano-Ríos M, Martínez Larrad MT, Villar NG,<br />

González López A, Téllez MJ, Fernández C. Leptin and adipose<br />

tissue maldistribution in HIV-infected male patients<br />

with predominant fat loss treated with antiretroviral therapy.<br />

J Acquir Immune Defic Syndr <strong>20</strong>02; 29: 32-40<br />

67 Igoudjil A, Abbey-Toby A, Begriche K, Grodet A, Chataign-<br />

2505 May 28, <strong>20</strong>11|Volume 17|Issue <strong>20</strong>|

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