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Traducción y terminología<br />

LAD-2 Acron. for leukocyte-adhesion deficiency 1. LAD-2<br />

lambda chain (or λ chain) In the context of immunoglobulins, one<br />

of the two forms of immunoglobulin light<br />

chains.<br />

Langerhans cells Dendritic cells found in the skin, able to act<br />

as effective antigen presenting cells.<br />

lectins Proteins, usually of plant origin, that can bind<br />

specifically to carbohydrates. Many lectins<br />

are mitogenic (i.e., can induce lymphocytes<br />

to divide), such as Con A and PHA.<br />

leukocyte-adhesion<br />

deficiency 1 (LAD-1)<br />

leukocyte-adhesion<br />

deficiency 2 (LAD-2)<br />

leukocyte functional<br />

antigens (LFA)<br />

An immune deficiency in which the<br />

adhesion molecule β2-integrin is not<br />

expressed.<br />

An immune deficiency in which fucosyl<br />

sugars (ligands to selectins) are not<br />

produced.<br />

Cell adhesion molecules initially defined<br />

with monoclonal antibodies. LFA-1 is<br />

a β2-integrin, particularly important in<br />

T-cell adhesion to endothelial cells and<br />

antigen-presenting cells. LFA-2 and LFA-<br />

3 are members of the immunoglobulin<br />

superfamily; LFA-3 is now called CD58.<br />

leukotrienes Vasoactive metabolites of arachidonic acid<br />

produced by the action of lipoxygenase,<br />

which promote inflammatory processes<br />

(e.g. chemotaxis, increased vascular<br />

permeability) and are produced by a variety<br />

of cell types including mast cells, basophils<br />

and macrophages.<br />

LFA-1, LFA-2 and LFA-3<br />

(see leukocyte functional<br />

antigens)<br />

Abbrev. for leukocyte functional antigens 1,<br />

2, and 3.<br />

Sigla de deficiência de<br />

adesão leucocitária 1.<br />

Geralmente é mantida<br />

como LAD-2, mas é<br />

aconselhável colocar o<br />

significado na primeira<br />

vez que o termo<br />

aparecer no texto.<br />

cadeia lambda ou<br />

cadeia λ<br />

LAD-2<br />

Sigla de deficiencia<br />

de adhesión del<br />

leucocito 1.<br />

Se mantiene<br />

generalmente la sigla<br />

en inglés, aunque se<br />

aconseja explicar su<br />

significado la primera<br />

vez que aparece.<br />

cadena lambda o<br />

cadena λ<br />

células de Langerhans células de Langerhans<br />

lectinas lectinas<br />

deficiência de adesão<br />

leucocitária 1 (LAD-<br />

1)<br />

deficiência de adesão<br />

leucocitária 2 (LAD-<br />

2)<br />

antígenos associados<br />

à função de leucócitos<br />

deficiencia de<br />

adhesión del<br />

leucocito 1 (LAD-1)<br />

deficiencia de<br />

adhesión del<br />

leucocito 2 (LAD-2)<br />

antígenos funcionales<br />

del leucocito<br />

leucotrienos leucotrienos<br />

LFA-1, LFA-2 e<br />

LFA-3<br />

Siglas para antígenos<br />

associados à função<br />

de leucócitos.<br />

Geralmente são<br />

mantidos como LFA-<br />

1,LFA-2 e LFA-3,<br />

respectivamente ,<br />

mas é aconselhável<br />

colocar o significado<br />

na primeira vez que<br />

o termo aparecer no<br />

texto.<br />

LFA-1, LFA-2 y<br />

LFA-3<br />

Siglas de antígenos<br />

funcionales del<br />

leucocito.<br />

Se mantiene<br />

generalmente la sigla<br />

en inglés, aunque se<br />

aconseja explicar su<br />

significado la primera<br />

vez que aparece.<br />

Panace@. Vol. VI, n. o 21-22. Septiembre-diciembre, 2005 261

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