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Enfermedades Inmunologicas Digestivas - Asociación de ...

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TRATAMIENTO DE HAI<br />

� Corticoi<strong>de</strong>s (1-2 mg/kg/día) solos o en combinación con<br />

azatioprina – 6-mercaptopurina<br />

� Asociación con otros inmunosupresores (tacrolimus-ciclosporinabu<strong>de</strong>soni<strong>de</strong>)<br />

� Sobrevida <strong>de</strong> mas <strong>de</strong>l 90% a 10 años en los pacientes con respuesta<br />

al tratamiento<br />

� Transplante hepático : sobrevida <strong>de</strong> 80-90 % a los 5 años<br />

Czaja, AJ. Diagnosis, prognosis, and treatment of classical autoimmune chronic active<br />

hepatitis. In: Autoimmune Liver Diseases, Krawitt, EL, Wiesner, RH (Eds), Raven Press,<br />

New York 1991. p.143.<br />

Feld, JJ, Dinh, H, Arenovich, T, et al. Autoimmune hepatitis: effect of symptoms and<br />

cirrhosis on natural history and outcome. Hepatology 2005. Al-Chalabi, T, Un<strong>de</strong>rhill, JA,<br />

Portmann, BC, et al. Effects of serum aspartate aminotransferase levels in patients with<br />

autoimmune hepatitis influence disease course and outcome. Clin Gastroenterol Hepatol<br />

2008.

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