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GENETIQUE ET SOMMEIL - SFRMS

GENETIQUE ET SOMMEIL - SFRMS

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Régulation circadienne (3)Action de l ’environnement (alternance L-O)sur rythmicité circadienne:-gène cry: Lumière associe prot CRYPTOCHROME et TIMdégradation de TIMdonc altère complexe PER-TIMEnvironnement non indispensable-gène dbt (double time): DBT se lie à PERDestruction via phosphorylation: durée complexe PER-TIMPermet une stabilité + précision du R circadienInteraction génétique - environnement

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