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AggiornAmenti in riAnimAzione e terApiA intensivA - Pacini Editore

AggiornAmenti in riAnimAzione e terApiA intensivA - Pacini Editore

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30<br />

pregnant and postpartum admissions to the <strong>in</strong>tensive<br />

care unit: a systematic review<br />

W. Pollock<br />

L. Rose<br />

C.L. Dennis<br />

School of Nurs<strong>in</strong>g<br />

and Midwifery, La Trobe<br />

University/Mercy Hospital<br />

for Women, Heidelberg,<br />

Australia<br />

PURPOSE: To determ<strong>in</strong>e the <strong>in</strong>cidence and characteristics of pregnant and<br />

postpartum women requir<strong>in</strong>g admission to an <strong>in</strong>tensive care unit (ICU).<br />

METhOdS: Medl<strong>in</strong>e, PubMed, EMBASE and CINAHL databases (1990-2008)<br />

were systematically searched for reports of women admitted to the ICU<br />

either pregnant or up to 6 weeks postpartum. Two reviewers <strong>in</strong>dependently<br />

determ<strong>in</strong>ed study eligibility and abstracted data.<br />

RESULTS: A total of 40 eligible studies report<strong>in</strong>g outcomes for 7,887 women<br />

were analysed. All studies were retrospective with the majority report<strong>in</strong>g<br />

data from a s<strong>in</strong>gle centre. The <strong>in</strong>cidence of ICU admission ranged<br />

from 0.7 to 13.5 per 1,000 deliveries. Pregnant or postpartum women accounted<br />

for 0.4-16.0% of ICU admissions <strong>in</strong> study centres. Hypertensive<br />

disorders of pregnancy were the most prevalent <strong>in</strong>dication for ICU admission<br />

[median 0.9 cases per 1,000 deliveries (range 0.2-6.7)]. There was<br />

no difference <strong>in</strong> the profile of ICU admission <strong>in</strong> develop<strong>in</strong>g compared to<br />

developed countries, except for the significantly higher maternal mortality<br />

rate <strong>in</strong> develop<strong>in</strong>g countries (median 3.3 vs. 14.0%, p = 0.002). Studies<br />

report<strong>in</strong>g patient outcomes subsequent to ICU admission are lack<strong>in</strong>g.<br />

COnCLUSIOnS: ICU admission of pregnant and postpartum women occurs<br />

<strong>in</strong>frequently, with obstetric conditions responsible for the majority of ICU<br />

admissions. The ICU admission profile of women was similar <strong>in</strong> developed<br />

and develop<strong>in</strong>g countries; however, the maternal mortality rate rema<strong>in</strong>s<br />

higher for ICUs <strong>in</strong> develop<strong>in</strong>g countries, support<strong>in</strong>g the need for ongo<strong>in</strong>g<br />

service delivery improvements. More studies are required to determ<strong>in</strong>e<br />

the impact of ICU admission for pregnant and postpartum women.<br />

Intensive Care Med 2010;36(9):1465-74

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