AggiornAmenti in riAnimAzione e terApiA intensivA - Pacini Editore
AggiornAmenti in riAnimAzione e terApiA intensivA - Pacini Editore
AggiornAmenti in riAnimAzione e terApiA intensivA - Pacini Editore
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30<br />
pregnant and postpartum admissions to the <strong>in</strong>tensive<br />
care unit: a systematic review<br />
W. Pollock<br />
L. Rose<br />
C.L. Dennis<br />
School of Nurs<strong>in</strong>g<br />
and Midwifery, La Trobe<br />
University/Mercy Hospital<br />
for Women, Heidelberg,<br />
Australia<br />
PURPOSE: To determ<strong>in</strong>e the <strong>in</strong>cidence and characteristics of pregnant and<br />
postpartum women requir<strong>in</strong>g admission to an <strong>in</strong>tensive care unit (ICU).<br />
METhOdS: Medl<strong>in</strong>e, PubMed, EMBASE and CINAHL databases (1990-2008)<br />
were systematically searched for reports of women admitted to the ICU<br />
either pregnant or up to 6 weeks postpartum. Two reviewers <strong>in</strong>dependently<br />
determ<strong>in</strong>ed study eligibility and abstracted data.<br />
RESULTS: A total of 40 eligible studies report<strong>in</strong>g outcomes for 7,887 women<br />
were analysed. All studies were retrospective with the majority report<strong>in</strong>g<br />
data from a s<strong>in</strong>gle centre. The <strong>in</strong>cidence of ICU admission ranged<br />
from 0.7 to 13.5 per 1,000 deliveries. Pregnant or postpartum women accounted<br />
for 0.4-16.0% of ICU admissions <strong>in</strong> study centres. Hypertensive<br />
disorders of pregnancy were the most prevalent <strong>in</strong>dication for ICU admission<br />
[median 0.9 cases per 1,000 deliveries (range 0.2-6.7)]. There was<br />
no difference <strong>in</strong> the profile of ICU admission <strong>in</strong> develop<strong>in</strong>g compared to<br />
developed countries, except for the significantly higher maternal mortality<br />
rate <strong>in</strong> develop<strong>in</strong>g countries (median 3.3 vs. 14.0%, p = 0.002). Studies<br />
report<strong>in</strong>g patient outcomes subsequent to ICU admission are lack<strong>in</strong>g.<br />
COnCLUSIOnS: ICU admission of pregnant and postpartum women occurs<br />
<strong>in</strong>frequently, with obstetric conditions responsible for the majority of ICU<br />
admissions. The ICU admission profile of women was similar <strong>in</strong> developed<br />
and develop<strong>in</strong>g countries; however, the maternal mortality rate rema<strong>in</strong>s<br />
higher for ICUs <strong>in</strong> develop<strong>in</strong>g countries, support<strong>in</strong>g the need for ongo<strong>in</strong>g<br />
service delivery improvements. More studies are required to determ<strong>in</strong>e<br />
the impact of ICU admission for pregnant and postpartum women.<br />
Intensive Care Med 2010;36(9):1465-74