TEV - profilassi e terapia - Facolta' di Medicina e Chirurgia - Chieti
TEV - profilassi e terapia - Facolta' di Medicina e Chirurgia - Chieti
TEV - profilassi e terapia - Facolta' di Medicina e Chirurgia - Chieti
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Terapia<br />
Approccio standard<br />
ENF 5.000-10.000 U e.v. (bolo) infusione continua<br />
EBPM s.c.<br />
1.250 U/h (PTT 60-80”)<br />
• Columbus Investigators<br />
Investigators. Low Low-molecular molecular-weight weight heparin in the treatment of patients with<br />
venous thromboembolism<br />
thromboembolism. N Engl J Med 1997 1997;337 337:657 657<br />
• Simmoneau G et al al. A comparison of low low-molecular molecular-weight weight heparin with unfractionated<br />
heparin for acute pulmonary embolism embolism. N Engl J Med 1997 1997;337 337:663 663<br />
• Merli G et al al. Subcutaneous enoxaparin once or twice daily compared with intravenous<br />
unfractionated heparin for treatment of venous thromboembolic <strong>di</strong>sease <strong>di</strong>sease. Ann Intern Med<br />
2001 2001;134 134:191 191<br />
• Bred<strong>di</strong>n HK et al al. Effects of a low low-molecular molecular-weight weight heparin on thrombus regression and<br />
recurrent thromboembolism in patients with deep deep-vein vein thrombosis<br />
thrombosis. N Engl J Med<br />
2001 2001;344 344:626 626
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