MICOBATTERI - Sezione di Microbiologia

COSTI
Caviedes L, et al. Rapid, efficient detection and drug susceptibility testing of Mycobacterium
tuberculosis in sputum by microscopic observation of broth cultures. The Tuberculosis Working
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Group in Peru. J Clin Microbiol. 2000 Mar;38(3):1203-8
Laboratorio del Hospital Alli Causai
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ABSTRACT
A collaborative project was established between the Alli Causai
Foundation in Ambato, Ecuador, and the University of Genova,
Italy, to introduce the microscopic observation drug susceptibility
(MODS) assay for the rapid identification of Mycobacterium
tuberculosis in Ecuador.
A total of 507 samples were evaluated during a 10-month
period, and DNA was extracted from each isolate and sent to
Genova for confirmatory molecular analysis.
M. tuberculosis was identified in 45 samples by MODS, and drug
resistance was observed in approximately 21% of the isolates,
with four multidrug-resistant strains detected in two patients.
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