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Diagnose en classificatie van acute leukemieën - UZ Leuven

Diagnose en classificatie van acute leukemieën - UZ Leuven

Diagnose en classificatie van acute leukemieën - UZ Leuven

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Promyelocyt<strong>en</strong> leukemie met t(15;17)<br />

(q21;q12)<br />

• 5-8 % <strong>van</strong> AML,<br />

associatie met AML M3:<br />

> 95%<br />

• leukemische cell<strong>en</strong> zijn<br />

abnormale<br />

promyelocyt<strong>en</strong><br />

• stollingsstoorniss<strong>en</strong><br />

• PML-RAR fusieg<strong>en</strong><br />

• beantwoordt aan<br />

retinoinezuur therapie<br />

• goede prognose<br />

Dana Van Kerkhov<strong>en</strong> <strong>en</strong> Caroline Brusselmans LAG

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