Biomasa este un termen generic care cuprinde o ... - ICECHIM

101produced in high quantum yields. The purpose of this paper is to study some metallicphthalocyanine sensitizers, to establish their correlation structure-photodynamic activity onSaccharomices Cerevisiae (SC). The photodynamic action of some Al and Zn sulfonatedphthalocyanines,with different sulphonation degree (AlS 2 Pc, AlS 3 Pc, AlS 4 Pc, ZnS 2 Pc,ZnS 3 Pc, ZnS 4 Pc), is discussed in this paper. All the photodynamic experiments are achievedon Saccharomices Cerevisiae (SC) culture cells (in vitro). The generation of reactive oxygenspecies is the initiator of apoptosis and cell death.6. LETHAL PHOTOSENSITIZATION INDUCED BY LASER RADIATIONNicoleta Herascu 1 , Mihaela Antonina Calin 1 , Rodica Mariana Ion 21National Institute of Research and Development for Optoelectronics INOE 20002INCDCP – ICECHIM, Splaiul Independentei 202, 060021-BucharestLethal photosensitization method represents an alternative treatment modality ofchronic diseases.Lethal photosensitization of microorganisms is based on the photosensitizeradministration, which in preferentially localized in the cell and then it is excited by opticalradiation with wavelength appropriate with the absorbance maximum of the photosensitizer.The excitation of the photosensitizers by optical radiation results in the production of cytotoxicspecies as singlet oxygen and free radicals. Due to the highly reactive nature of these species,they will lead to a certain biological effects resulting in the microorganism death by aselectivity action on the target prockaryotic cells.Till now, have been made several studies, especially in vitro, to inactivatemicroorganisms as bacteria, fungi, yeast and virus using a large variety of photosensitizers andsome laser sources.In this study will be provided an overview regarding the state-of-the art of the lethalphotosensitizer development method in terms of photosensitizers and laser sources used toinactivated different microorganisms.