(MRSP) hos svenska hundar - SVA

INNEHÅLLSFÖRTECKNINGTack ......................................................................................................................... 6Ordlista ..................................................................................................................... 7Sammanfattning ....................................................................................................... 8Abstract .................................................................................................................... 8Inledning .................................................................................................................. 9Syfte ................................................................................................................... 11Bakgrundsfakta ...................................................................................................... 11Staphylococcus pseudintermedius ..................................................................... 11Vad utmärker en meticillinresistent Staphylococcus pseudintermedius(MRSP)? ............................................................................................................ 11MRSP och MRSA .............................................................................................. 13Bärarskap och transient bärarskap ..................................................................... 13Betalaktamer ...................................................................................................... 14Hur sprids och etableras MRSP? ....................................................................... 14Antibiotikaanvändning i Sverige ....................................................................... 16Material och metoder ............................................................................................. 16Material .............................................................................................................. 16Provtagningsmetod ........................................................................................ 17Metod ................................................................................................................. 17Resultat .................................................................................................................. 19Rådata ................................................................................................................ 19Bärarskap ........................................................................................................... 20Tidsaspekten .................................................................................................. 20Lokalisation ................................................................................................... 20Klinik ................................................................................................................. 21Diagnos .......................................................................................................... 21Kliniska symptom .......................................................................................... 21Stationärvård .................................................................................................. 22Kön, ras och ålder .......................................................................................... 22Antibiotikabehandling ....................................................................................... 22Behandlingsstatistik ....................................................................................... 22Behandlingstider ............................................................................................ 23Tetracyklinbehandling ................................................................................... 23Diskussion .............................................................................................................. 23Varför är vissa diagnoser mer vanliga än andra? ........................................... 25Kliniska symptom och bärarskap ................................................................... 25Djursjukhus som potentiella smittreservoarer ............................................... 26MRSP - ett nytt problem för djursjukvården? ............................................... 26Antibiotikabehandling och resistensutveckling ................................................. 27Antibiotikapolicy ........................................................................................... 28MRSP en potentiell zoonos ............................................................................ 28Avgränsningar och felkällor .............................................................................. 28Konklusion ............................................................................................................. 29Framtida forskning ................................................................................................. 29Litteraturförteckning .............................................................................................. 30Bilagor ................................................................................................................... 32Bilaga 1 .......................................................................................................... 32Bilaga 2 .......................................................................................................... 383